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Found 16 of ic50 for monomerid = 161396
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161396(US10124003, Ex. Compound 9 | US10835536, Ex. Comp ...)
Affinity DataIC50:  0.100nMAssay Description:The inhibitory effect of the compounds on FGFR3 kinase activity was measured according to the method of Test Example 3. Purified recombinant human FG...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161396(US10124003, Ex. Compound 9 | US10835536, Ex. Comp ...)
Affinity DataIC50:  0.300nMAssay Description:Purified recombinant human FGFR3 protein was purchased from Carna Biosciences, Inc. When setting conditions for the measurement of the inhibitory ef...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161396(US10124003, Ex. Compound 9 | US10835536, Ex. Comp ...)
Affinity DataIC50:  0.300nMAssay Description:The inhibitory effect of the compounds on FGFR3 kinase activity was measured according to the method of Test Example 3. Purified recombinant human FG...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161396(US10124003, Ex. Compound 9 | US10835536, Ex. Comp ...)
Affinity DataIC50: <0.300nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161396(US10124003, Ex. Compound 9 | US10835536, Ex. Comp ...)
Affinity DataIC50:  1.10nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161396(US10124003, Ex. Compound 9 | US10835536, Ex. Comp ...)
Affinity DataIC50:  1.10nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161396(US10124003, Ex. Compound 9 | US10835536, Ex. Comp ...)
Affinity DataIC50:  1.10nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161396(US10124003, Ex. Compound 9 | US10835536, Ex. Comp ...)
Affinity DataIC50:  1.10nMpH: 7.5 T: 2°CAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161396(US10124003, Ex. Compound 9 | US10835536, Ex. Comp ...)
Affinity DataIC50:  1.20nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR1 kinase activity, a biotinylated peptide (biotin-EEPLYW...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161396(US10124003, Ex. Compound 9 | US10835536, Ex. Comp ...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human recombinant cytoplasmic domain FGFR2 (8 to 134 residues) incubated for 120 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161396(US10124003, Ex. Compound 9 | US10835536, Ex. Comp ...)
Affinity DataIC50:  1.70nMAssay Description:The inhibitory effect of the compounds on FGFR4 kinase activity was measured according to the method of Test Example 3. Purified recombinant human FG...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161396(US10124003, Ex. Compound 9 | US10835536, Ex. Comp ...)
Affinity DataIC50:  3.20nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR1 kinase activity, a biotinylated peptide (biotin-EEPLYW...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161396(US10124003, Ex. Compound 9 | US10835536, Ex. Comp ...)
Affinity DataIC50:  3.20nMAssay Description:Purified recombinant human FGFR4 protein was purchased from Carna Biosciences, Inc. When setting conditions for the measurement of the inhibitory ef...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161396(US10124003, Ex. Compound 9 | US10835536, Ex. Comp ...)
Affinity DataIC50:  4.90nMAssay Description:The inhibitory effect of the compounds on FGFR4 kinase activity was measured according to the method of Test Example 3. Purified recombinant human FG...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161396(US10124003, Ex. Compound 9 | US10835536, Ex. Comp ...)
Affinity DataIC50:  4.90nMAssay Description:Purified recombinant human FGFR4 protein was purchased from Carna Biosciences, Inc. When setting conditions for the measurement of the inhibitory ef...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM161396(US10124003, Ex. Compound 9 | US10835536, Ex. Comp ...)
Affinity DataIC50:  3.03E+3nMAssay Description:Inhibition of N-terminal GST tagged recombinant human VEGFR2 (aa805 to 1356 residues) expressed in baculovirus expression system using Poly- (Glu4:Ty...More data for this Ligand-Target Pair
In DepthDetails PubMed