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Found 6 of ic50 for monomerid = 254583
TargetGlutathione S-transferase P/Lysine-specific histone demethylase 1A [158-852](Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM254583(US9469597, 42 | US9670136, 42 N1-((trans)-2-(4-(1H...)
Affinity DataIC50:  27nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM254583(US9469597, 42 | US9670136, 42 N1-((trans)-2-(4-(1H...)
Affinity DataIC50:  27nMpH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM254583(US9469597, 42 | US9670136, 42 N1-((trans)-2-(4-(1H...)
Affinity DataIC50:  8.48E+3nMAssay Description:Briefly, a fixed amount of MAO (0.25 μg for MAO-A and 0.5 μg for MAO-B) was incubated on ice for 15 minutes in the reaction buffer, in the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM254583(US9469597, 42 | US9670136, 42 N1-((trans)-2-(4-(1H...)
Affinity DataIC50:  8.48E+3nMpH: 7.5 T: 2°CAssay Description:In order to monitor MAO enzymatic activities and/or their inhibition rate by inhibitor(s) of interest, a fluorescence-based (inhibitor)-screening ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM254583(US9469597, 42 | US9670136, 42 N1-((trans)-2-(4-(1H...)
Affinity DataIC50:  8.93E+3nMAssay Description:Briefly, a fixed amount of MAO (0.25 μg for MAO-A and 0.5 μg for MAO-B) was incubated on ice for 15 minutes in the reaction buffer, in the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM254583(US9469597, 42 | US9670136, 42 N1-((trans)-2-(4-(1H...)
Affinity DataIC50:  8.93E+3nMpH: 7.5 T: 2°CAssay Description:In order to monitor MAO enzymatic activities and/or their inhibition rate by inhibitor(s) of interest, a fluorescence-based (inhibitor)-screening ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent