TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University
Curated by ChEMBL
Mansoura University
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University
Curated by ChEMBL
Mansoura University
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University
Curated by ChEMBL
Mansoura University
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant VEGFR2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University
Curated by ChEMBL
Mansoura University
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University
Curated by ChEMBL
Mansoura University
Curated by ChEMBL
Affinity DataIC50: 30nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University
Curated by ChEMBL
Mansoura University
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University
Curated by ChEMBL
Mansoura University
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of GST-tagged human VEGFR2 C-terminal domain using (biotin-aminohexyl-EEEEYFELVAKKKK-NH2 substrate incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University
Curated by ChEMBL
Mansoura University
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of VEGFR-2 (unknown origin) after 40 mins by kinase-Glo assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University
Curated by ChEMBL
Mansoura University
Curated by ChEMBL
Affinity DataIC50: 43nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of VEGFR-3 (unknown origin) after 40 mins by kinase-Glo assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of VEGFR3 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of VEGFR3 (unknown origin)More data for this Ligand-Target Pair
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Technical University Of Dortmund
Curated by ChEMBL
Technical University Of Dortmund
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of wild type DDR2 (unknown origin) preincubated for 30 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Tianjin University
Curated by ChEMBL
Tianjin University
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of PDGFR-alpha tyrosine kinase (unknown origin) after 30 mins by HTRF methodMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of PDGFRbeta (unknown origin) after 40 mins by kinase-Glo assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of PDGFRbeta (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:Inhibition of VEGFR-1 (unknown origin) after 40 mins by kinase-Glo assayMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: 118nMAssay Description:Inhibition of C-kit (unknown origin) after 40 mins by kinase-Glo assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
West China Hospital Of Sichuan University
Curated by ChEMBL
West China Hospital Of Sichuan University
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of FGFR2 (unknown origin)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
West China Hospital Of Sichuan University
Curated by ChEMBL
West China Hospital Of Sichuan University
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
West China Hospital Of Sichuan University
Curated by ChEMBL
West China Hospital Of Sichuan University
Curated by ChEMBL
Affinity DataIC50: 163nMAssay Description:Inhibition of FGFR1 (unknown origin) after 40 mins by kinase-Glo assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: 274nMAssay Description:Inhibition of C-fms (unknown origin) after 40 mins by kinase-Glo assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Shandong Institute of Pharmaceutical Industry
Shandong Institute of Pharmaceutical Industry
Affinity DataIC50: 620nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Fudan University
Curated by ChEMBL
Fudan University
Curated by ChEMBL
Affinity DataIC50: 873nMAssay Description:Inhibition of RIPK1 in human HT-29 cells assessed as reduction in TNFalpha-induced necroptosis incubated for 14 to 24 hrs in presence of Smac mimetic...More data for this Ligand-Target Pair
Affinity DataIC50: 930nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
TargetReceptor protein-tyrosine kinase(Homo sapiens (Human))
Shandong Institute of Pharmaceutical Industry
Shandong Institute of Pharmaceutical Industry
Affinity DataIC50: 5.95E+3nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair