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Found 10 of ic50 for monomerid = 27708
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Fujisawa Pharmaceutical

LigandPNGBDBM27708(8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...)
Affinity DataIC50:  13nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Fujisawa Pharmaceutical

LigandPNGBDBM27708(8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Fujisawa Pharmaceutical

LigandPNGBDBM27708(8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...)
Affinity DataIC50:  13nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Fujisawa Pharmaceutical

LigandPNGBDBM27708(8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Fujisawa Pharmaceutical

LigandPNGBDBM27708(8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...)
Affinity DataIC50:  13nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Fujisawa Pharmaceutical

LigandPNGBDBM27708(8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...)
Affinity DataIC50:  65nMAssay Description:Inhibition of human recombinant N-terminal 6His-6Lys-TEV tagged PARP1 full length expressed in pFastBac expression system incubated for 4 hrs by fluo...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Johns Hopkins University Brain Science Institute

Curated by ChEMBL
LigandPNGBDBM27708(8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...)
Affinity DataIC50:  500nMAssay Description:Inhibition of PARP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Fujisawa Pharmaceutical

LigandPNGBDBM27708(8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...)
Affinity DataIC50:  500nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM27708(8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Johns Hopkins University Brain Science Institute

Curated by ChEMBL
LigandPNGBDBM27708(8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human recombinant N-terminal Avi-6His-TEV tagged PARP2 full length expressed in pFastBac expression system incubated for 4 hrs by fluor...More data for this Ligand-Target Pair
In DepthDetails PubMed