Affinity DataIC50: 13nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant PARP1More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of human recombinant N-terminal 6His-6Lys-TEV tagged PARP1 full length expressed in pFastBac expression system incubated for 4 hrs by fluo...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
Affinity DataIC50: 500nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
Johns Hopkins University Brain Science Institute
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant N-terminal Avi-6His-TEV tagged PARP2 full length expressed in pFastBac expression system incubated for 4 hrs by fluor...More data for this Ligand-Target Pair