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Found 5 of ic50 for monomerid = 283414
TargetPlasma kallikrein(Homo sapiens (Human))
Lifesci Pharmaceuticals

US Patent
LigandPNGBDBM283414(3-chloro-6-((4-(((6-fluoro-1H-indol-5- yl)methyl)c...)
Affinity DataIC50: <100nMpH: 7.5Assay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Lifesci Pharmaceuticals

US Patent
LigandPNGBDBM283414(3-chloro-6-((4-(((6-fluoro-1H-indol-5- yl)methyl)c...)
Affinity DataIC50: <100nMAssay Description:The ability of the compounds disclosed herein to inhibit human plasma kallikrein activity was quantified according to the procedures below.A 10 mM so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Lifesci Pharmaceuticals

US Patent
LigandPNGBDBM283414(3-chloro-6-((4-(((6-fluoro-1H-indol-5- yl)methyl)c...)
Affinity DataIC50: <100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Lifesci Pharmaceuticals

US Patent
LigandPNGBDBM283414(3-chloro-6-((4-(((6-fluoro-1H-indol-5- yl)methyl)c...)
Affinity DataIC50: <100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Lifesci Pharmaceuticals

US Patent
LigandPNGBDBM283414(3-chloro-6-((4-(((6-fluoro-1H-indol-5- yl)methyl)c...)
Affinity DataIC50: <100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent