Compile Data Set for Download or QSAR
maximum 50k data
Found 5 of ic50 for monomerid = 286987
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM286987(8-(3-(4-acryloylpiperazin-1-yl)propyl)-2-((cyclopr...)
Affinity DataIC50:  0.100nMT: 2°CAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM286987(8-(3-(4-acryloylpiperazin-1-yl)propyl)-2-((cyclopr...)
Affinity DataIC50:  0.100nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM286987(8-(3-(4-acryloylpiperazin-1-yl)propyl)-2-((cyclopr...)
Affinity DataIC50:  0.100nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM286987(8-(3-(4-acryloylpiperazin-1-yl)propyl)-2-((cyclopr...)
Affinity DataIC50:  3.30nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM286987(8-(3-(4-acryloylpiperazin-1-yl)propyl)-2-((cyclopr...)
Affinity DataIC50:  3.30nMAssay Description:The cell-based effects of FGFR inhibitors were determined by measuring inhibition of FGFR-dependent cell line growth. The cell lines SNU-16 was used ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent