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Found 12 of ic50 for monomerid = 29388
TargetProthrombin(Homo sapiens (Human))
Link£Ping University

Curated by ChEMBL
LigandPNGBDBM29388(Exanta | Melagatran | US11584714, Compound 999)
Affinity DataIC50:  4.70nMAssay Description:In vitro inhibitory concentration of compound against human thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Link£Ping University

Curated by ChEMBL
LigandPNGBDBM29388(Exanta | Melagatran | US11584714, Compound 999)
Affinity DataIC50:  8nMAssay Description:The thrombin inhibitor potency (IC50) was measured with a chromogenic substrate method in a robotic microplate processor, using 96-well, half-volume ...More data for this Ligand-Target Pair
TargetSerine protease 1(Bos taurus (bovine))
Basf

Curated by ChEMBL
LigandPNGBDBM29388(Exanta | Melagatran | US11584714, Compound 999)
Affinity DataIC50:  11nMAssay Description:In vitro inhibitory activity against trypsinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Link£Ping University

Curated by ChEMBL
LigandPNGBDBM29388(Exanta | Melagatran | US11584714, Compound 999)
Affinity DataIC50:  69nMAssay Description:In vitro inhibitory activity against thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Link£Ping University

Curated by ChEMBL
LigandPNGBDBM29388(Exanta | Melagatran | US11584714, Compound 999)
Affinity DataIC50:  69nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Link£Ping University

Curated by ChEMBL
LigandPNGBDBM29388(Exanta | Melagatran | US11584714, Compound 999)
Affinity DataIC50:  69.2nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM29388(Exanta | Melagatran | US11584714, Compound 999)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM29388(Exanta | Melagatran | US11584714, Compound 999)
Affinity DataIC50:  3.06E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Link£Ping University

Curated by ChEMBL
LigandPNGBDBM29388(Exanta | Melagatran | US11584714, Compound 999)
Affinity DataIC50:  4.70E+3nMAssay Description:In vitro for the inhibition of thrombinMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM29388(Exanta | Melagatran | US11584714, Compound 999)
Affinity DataIC50:  1.73E+4nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM29388(Exanta | Melagatran | US11584714, Compound 999)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human coagulation factor 11a using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM29388(Exanta | Melagatran | US11584714, Compound 999)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed