Compile Data Set for Download or QSAR
maximum 50k data
Found 3 of ic50 for monomerid = 29788
TargetBeta-secretase 1(Homo sapiens (Human))
Gsk

LigandPNGBDBM29788(7,6,5 tricyclic sulfonamide, 34)
Affinity DataIC50:  14nMpH: 4.5 T: 2°CAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM29788(7,6,5 tricyclic sulfonamide, 34)
Affinity DataIC50:  1.05E+3nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Gsk

LigandPNGBDBM29788(7,6,5 tricyclic sulfonamide, 34)
Affinity DataIC50:  1.41E+4nMAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed