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Compile Data Set for Download or QSAR
maximum 50k data
Found
1
of ic50 for monomerid = 326292
Target
E3 ubiquitin-protein ligase Mdm2 [17-125]
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM326292
(6-(1-benzofuran-5-yl)- 4-{[(1R)-1- cyclobutylethyl...)
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Affinity Data
IC50: 105nM
Assay Description:
Methods: An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM...
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Ligand Info
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US Patent
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