Compile Data Set for Download or QSAR
maximum 50k data
Found 7 of ic50 for monomerid = 361472
TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM361472(3-((1R,3R)-1- (3,5-difluoro- 2-(2-((3- fluoropropy...)
Affinity DataIC50:  0.0710nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM361472(3-((1R,3R)-1- (3,5-difluoro- 2-(2-((3- fluoropropy...)
Affinity DataIC50:  0.960nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha—LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetEstrogen receptor [307-554](Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM361472(3-((1R,3R)-1- (3,5-difluoro- 2-(2-((3- fluoropropy...)
Affinity DataIC50:  0.960nMAssay Description:ERα: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM361472(3-((1R,3R)-1- (3,5-difluoro- 2-(2-((3- fluoropropy...)
Affinity DataIC50:  0.960nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM361472(3-((1R,3R)-1- (3,5-difluoro- 2-(2-((3- fluoropropy...)
Affinity DataIC50:  6.10E+3nMAssay Description:hERG: The purpose of the hERG binding assay is to evaluate the effects of test compounds on the voltage-dependent potassium channel encoded by the hu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM361472(3-((1R,3R)-1- (3,5-difluoro- 2-(2-((3- fluoropropy...)
Affinity DataIC50:  6.10E+3nMAssay Description:hERG (human ether a go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM361472(3-((1R,3R)-1- (3,5-difluoro- 2-(2-((3- fluoropropy...)
Affinity DataIC50:  6.10E+3nMAssay Description:hERG (human ether a go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent