Compile Data Set for Download or QSAR
maximum 50k data
Found 8 of ic50 for monomerid = 480928
TargetPantetheinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM480928(8-oxa-2-azaspiro[4.5]dec l{2-[(pyrazin-2-ylmethyl)...)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of recombinant N-terminal FLAG/His6-tagged human vanin-1 expressed in CHO cells using Pantetheine-7-amino-4-trifluoromethykournarin as sub...More data for this Ligand-Target Pair
TargetPantetheinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM480928(8-oxa-2-azaspiro[4.5]dec l{2-[(pyrazin-2-ylmethyl)...)
Affinity DataIC50:  7.66nMAssay Description:The test inhibitors were solubilized in DMSO to a stock concentration of 30 mM. On the day of the assay, dose response plates were prepared by diluti...More data for this Ligand-Target Pair
TargetPantetheinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM480928(8-oxa-2-azaspiro[4.5]dec l{2-[(pyrazin-2-ylmethyl)...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human plasma vanin-1 using pantetheine-7-amino-4-trifluoromethykournarin as substrate preincubated for 30 mins followed by substrate ad...More data for this Ligand-Target Pair
TargetVanin 1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480928(8-oxa-2-azaspiro[4.5]dec l{2-[(pyrazin-2-ylmethyl)...)
Affinity DataIC50:  12nMAssay Description:Inhibition of Wistar han rat serum vanin-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPantetheinase(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480928(8-oxa-2-azaspiro[4.5]dec l{2-[(pyrazin-2-ylmethyl)...)
Affinity DataIC50:  25nMAssay Description:Inhibition of mouse vanin-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPantetheinase(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480928(8-oxa-2-azaspiro[4.5]dec l{2-[(pyrazin-2-ylmethyl)...)
Affinity DataIC50:  53nMAssay Description:Inhibition of mouse plasma vanin-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM480928(8-oxa-2-azaspiro[4.5]dec l{2-[(pyrazin-2-ylmethyl)...)
Affinity DataIC50: >100nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBiotinidase(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480928(8-oxa-2-azaspiro[4.5]dec l{2-[(pyrazin-2-ylmethyl)...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed