Compile Data Set for Download or QSAR
maximum 50k data
Found 6 of ic50 for monomerid = 50026603
TargetMu-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50026603(Buprenorphine | CHEBI:3216)
Affinity DataIC50:  0.590nMAssay Description:Activity at human cloned mu opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDelta-type opioid receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50026603(Buprenorphine | CHEBI:3216)
Affinity DataIC50:  0.900nMAssay Description:Binding affinity against delta-opiate receptor (human) using [3H]-DPDPE radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetKappa-type opioid receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50026603(Buprenorphine | CHEBI:3216)
Affinity DataIC50:  1.20nMAssay Description:Binding affinity against opioid receptor kappa 1 using [3H]- U-69,593 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50026603(Buprenorphine | CHEBI:3216)
Affinity DataIC50:  1.70nMAssay Description:Binding affinity against mu-opiate receptor (human) using [3H]DAMGO radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50026603(Buprenorphine | CHEBI:3216)
Affinity DataIC50:  8.10nMAssay Description:Agonist activity at kappa opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50026603(Buprenorphine | CHEBI:3216)
Affinity DataIC50:  15nMAssay Description:Activity at human cloned kappa opioid receptor expressed in CHO cells assessed as inhibition of U50488-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank