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Found 3 of ic50 for monomerid = 50054260
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research and Technology

US Patent
LigandPNGBDBM50054260(CHEMBL3319379 | US9522881, 11a-24 L97L05 | US98445...)
Affinity DataIC50:  380nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research and Technology

US Patent
LigandPNGBDBM50054260(CHEMBL3319379 | US9522881, 11a-24 L97L05 | US98445...)
Affinity DataIC50:  380nMAssay Description:PTP assays were conducted as previously described in Kontaridis et al., J Biol Chem. 2006; 281:6785-6792, using para-nitrophenyl phosphate (pNPP, obt...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50054260(CHEMBL3319379 | US9522881, 11a-24 L97L05 | US98445...)
Affinity DataIC50:  380nMAssay Description:Inhibition of SHP2 (unknown origin) using p-nitrophenyl phosphate substrate by microplate spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed