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Found 5 of ic50 for monomerid = 50095441
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
Epizyme

Curated by ChEMBL
LigandPNGBDBM50095441(CHEMBL3589039)
Affinity DataIC50:  10nMAssay Description:Inhibition of FLAG and hexa-histidine tagged full-length human PRMT6 expressed in HEK293F cells pre-incubated for 30 mins before addition of a [3H]SA...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Epizyme

Curated by ChEMBL
LigandPNGBDBM50095441(CHEMBL3589039)
Affinity DataIC50:  119nMAssay Description:Inhibition of N-terminal GST tagged full-length human PRMT1 expressed in high five insect cells pre-incubated for 30 mins before addition of a [3H]SA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 8(Homo sapiens (Human))
Epizyme

Curated by ChEMBL
LigandPNGBDBM50095441(CHEMBL3589039)
Affinity DataIC50:  223nMAssay Description:Inhibition of N-terminal GST tagged full-length human PRMT8 expressed in Escherichia coli (BL21(DE3) pre-incubated for 30 mins before addition of a [...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
Epizyme

Curated by ChEMBL
LigandPNGBDBM50095441(CHEMBL3589039)
Affinity DataIC50:  637nMAssay Description:Inhibition of his-tagged PRMT6 (unknown origin) expressed in human A375 cells assessed as reduction in H3R2 methylation at 0.01 to 20 uM incubated fo...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Epizyme

Curated by ChEMBL
LigandPNGBDBM50095441(CHEMBL3589039)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of PRMT1 in human A375 cells assessed as effect on monomethyl R*GG motif methylation at 0.01 to 20 uM incubated for 48 hrs by Western blot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed