Compile Data Set for Download or QSAR
maximum 50k data
Found 5 of ic50 for monomerid = 50096325
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50096325(CHEMBL3577120)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of wild type CRAF (unknown origin) assessed as ADP formation measured for 5 hrs by pyruvate kinase/lactate dehydrogenase coupled assay in ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50096325(CHEMBL3577120)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant BRAF V600E mutant (unknown origin) assessed as ADP formation measured for 5 hrs by pyruvate kinase/lactate dehydrogenase co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50096325(CHEMBL3577120)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of wild type BRAF (unknown origin) assessed as ADP formation measured for 5 hrs by pyruvate kinase/lactate dehydrogenase coupled assay in ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50096325(CHEMBL3577120)
Affinity DataIC50:  33nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50096325(CHEMBL3577120)
Affinity DataIC50:  82nMAssay Description:Inhibition of BRAF V600E mutant in human A375 cells assessed as inhibition of ERK phosphorylation measured after 72 hrs by ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed