Compile Data Set for Download or QSAR
Found 2 of ic50 for monomerid = 50104992
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50104992(CHEMBL114700 | N-[6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Show SMILES COc1cccc(Oc2c(NS(=O)(=O)c3ccc(cc3)C(C)(C)C)ncnc2OCCOc2ncc(Br)cn2)c1
Show InChI InChI=1S/C27H28BrN5O6S/c1-27(2,3)18-8-10-22(11-9-18)40(34,35)33-24-23(39-21-7-5-6-20(14-21)36-4)25(32-17-31-24)37-12-13-38-26-29-15-19(28)16-30-26/h5-11,14-17H,12-13H2,1-4H3,(H,31,32,33)
Affinity DataIC50: 0.0510nMAssay Description:In vitro inhibition of [125 I]ET-1 binding to Endothelin A receptor in porcine aortic membraneMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50104992(CHEMBL114700 | N-[6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Show SMILES COc1cccc(Oc2c(NS(=O)(=O)c3ccc(cc3)C(C)(C)C)ncnc2OCCOc2ncc(Br)cn2)c1
Show InChI InChI=1S/C27H28BrN5O6S/c1-27(2,3)18-8-10-22(11-9-18)40(34,35)33-24-23(39-21-7-5-6-20(14-21)36-4)25(32-17-31-24)37-12-13-38-26-29-15-19(28)16-30-26/h5-11,14-17H,12-13H2,1-4H3,(H,31,32,33)
Affinity DataIC50: 0.0510nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair