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Found 12 of ic50 for monomerid = 50110484
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50110484(3-((3-fluoro-5-(1-methoxycyclohexyl)phenoxy)methyl...)
Affinity DataIC50:  3nMAssay Description:Inhibition constant against arachidonate 5-lipoxygenase More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50110484(3-((3-fluoro-5-(1-methoxycyclohexyl)phenoxy)methyl...)
Affinity DataIC50:  3nMAssay Description:The compound was evaluated for its inhibitory activity against 5-lipoxygenase using granulocytes-type cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50110484(3-((3-fluoro-5-(1-methoxycyclohexyl)phenoxy)methyl...)
Affinity DataIC50: >10nMAssay Description:Inhibitory concentration against prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50110484(3-((3-fluoro-5-(1-methoxycyclohexyl)phenoxy)methyl...)
Affinity DataIC50:  45nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50110484(3-((3-fluoro-5-(1-methoxycyclohexyl)phenoxy)methyl...)
Affinity DataIC50:  50nMAssay Description:Inhibitory concentration against prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50110484(3-((3-fluoro-5-(1-methoxycyclohexyl)phenoxy)methyl...)
Affinity DataIC50:  50nMAssay Description:The compound was evaluated for its inhibitory activity against Prostaglandin G/H synthase 2 using osteosarcomes cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50110484(3-((3-fluoro-5-(1-methoxycyclohexyl)phenoxy)methyl...)
Affinity DataIC50:  200nMAssay Description:Inhibition of 5-lipoxygenase in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50110484(3-((3-fluoro-5-(1-methoxycyclohexyl)phenoxy)methyl...)
Affinity DataIC50:  300nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50110484(3-((3-fluoro-5-(1-methoxycyclohexyl)phenoxy)methyl...)
Affinity DataIC50:  9.70E+3nMAssay Description:Inhibition of COX2 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50110484(3-((3-fluoro-5-(1-methoxycyclohexyl)phenoxy)methyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:The compound was evaluated for its inhibitory activity against Prostaglandin G/H synthase 1 using monocytes-like cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50110484(3-((3-fluoro-5-(1-methoxycyclohexyl)phenoxy)methyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of COX1 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50110484(3-((3-fluoro-5-(1-methoxycyclohexyl)phenoxy)methyl...)
Affinity DataIC50:  2.61E+4nMAssay Description:Inhibition of COX1 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed