Compile Data Set for Download or QSAR
maximum 50k data
Found 4 of ic50 for monomerid = 50145685
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
National Heart And Lung Institute

Curated by ChEMBL
LigandPNGBDBM50145685((4,6-Dimethyl-pyrimidin-5-yl)-(4-{(S)-4-[(R)-2-met...)
Affinity DataIC50:  0.450nMAssay Description:Binding affinity to CCR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Mus musculus)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50145685((4,6-Dimethyl-pyrimidin-5-yl)-(4-{(S)-4-[(R)-2-met...)
Affinity DataIC50:  0.910nMAssay Description:Displacement of [125I]-RANTES from CCR5 in mouse NIH/3T3 cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
National Heart And Lung Institute

Curated by ChEMBL
LigandPNGBDBM50145685((4,6-Dimethyl-pyrimidin-5-yl)-(4-{(S)-4-[(R)-2-met...)
Affinity DataIC50:  1.20nMAssay Description:Antagonist activity at CCR5 in IL-10 stimulated human PBMC cells assessed as MIP-1beta induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
National Heart And Lung Institute

Curated by ChEMBL
LigandPNGBDBM50145685((4,6-Dimethyl-pyrimidin-5-yl)-(4-{(S)-4-[(R)-2-met...)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 in IL-10-stimulated human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed