Compile Data Set for Download or QSAR
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Found 9 of ic50 for monomerid = 50158383
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50158383(2-((8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-2,...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 10(Homo sapiens (Human))
Ruhr-University Bochum

Curated by ChEMBL
LigandPNGBDBM50158383(2-((8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-2,...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant soluble adenylyl cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50158383(2-((8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-2,...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of His-tagged full length human Tdp1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50158383(2-((8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-2,...)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50158383(2-((8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-2,...)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of human Tdp1 expressed in Escherichia coli assessed as blockade of enzyme-mediated hydrolysis of phosphodiester linkage between tyrosine ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50158383(2-((8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-2,...)
Affinity DataIC50:  8.43E+3nMAssay Description:Inhibition of human tyrosyl-DNA phosphodiesterase 1 after 30 mins by alpha high throughput screening assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50158383(2-((8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-2,...)
Affinity DataIC50:  1.39E+4nMAssay Description:Inhibition of human AICAR TfaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRhodopsin(Bos taurus)
Washington University

Curated by ChEMBL
LigandPNGBDBM50158383(2-((8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-2,...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of bovine retinal rod outer-segment photoactivated rhodopsin-transducin interaction by transducin release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase(Spirulina platensis)
Ruhr-University Bochum

Curated by ChEMBL
LigandPNGBDBM50158383(2-((8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-2,...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of Spirulina platensis adenylyl cyclase assessed as cAMP level by cAMP immunogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed