TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N315AMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S118NMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N315DMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q189PMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E295AMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR M24IMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q189AMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E295QMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q189KMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR L112AMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR L112FMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Y284FMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S203QMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S203EMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S186DMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E295KMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR T51AMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S203KMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S118AMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E111QMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR L112KMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR A50TMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR H182EMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR T190KMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR K191EMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S168IMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N27EMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S124AMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S168AMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 4.10nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S186KMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 4.10nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR L117AMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR F272LMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E111AMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D293NMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 4.80nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D293KMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR M24TMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S203PMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 5.60nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR F313LMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 5.70nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D293AMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 5.80nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N27AMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 5.90nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR M24AMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 6.10nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D293EMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR L300VMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 6.60nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR H182AMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 8.10nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from human wild type GnRHRMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 8.20nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR K115QMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 10.1nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q208DMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 10.3nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR W280FMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 10.5nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E111KMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataIC50: 12.4nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N305KMore data for this Ligand-Target Pair