TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb R & D
Curated by ChEMBL
Bristol-Myers Squibb R & D
Curated by ChEMBL
Affinity DataIC50: 0.0200nMAssay Description:Displacement of [125I]CGRP from CGRP receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb R & D
Curated by ChEMBL
Bristol-Myers Squibb R & D
Curated by ChEMBL
Affinity DataIC50: 0.0300nMAssay Description:Antagonist activity against human CGRP receptorMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals
Curated by ChEMBL
Biohaven Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of human CLR/RAMP1More data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Biohaven Pharmaceuticals
Curated by ChEMBL
Biohaven Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Antagonist activity at human cloned CLR/RAMP1 receptor expressed in E10 cells measured as inhibition of CGRP-mediated cAMP productionMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb R & D
Curated by ChEMBL
Bristol-Myers Squibb R & D
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Antagonist activity at CGRP receptor in human SK-N-MC cells assessed as inhibition of CGRP-stimulated cAMP production preincubated for 30 mins follow...More data for this Ligand-Target Pair