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Found 11 of ic50 for monomerid = 50209568
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50209568(4',7,8-trihydroxyisoflavone | 7,8,4'-trihydroxyiso...)
Affinity DataIC50:  670nMAssay Description:Inhibition of PFKFB3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50209568(4',7,8-trihydroxyisoflavone | 7,8,4'-trihydroxyiso...)
Affinity DataIC50:  670nMAssay Description:Inhibition of PFKFB3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universidad De Santiago

LigandPNGBDBM50209568(4',7,8-trihydroxyisoflavone | 7,8,4'-trihydroxyiso...)
Affinity DataIC50:  900nMpH: 7.3 T: 2°CAssay Description:The reactions were done in a volume of 2 mL and constantly stirred using a magnetic stir bar at room temperature (23 °C). Reactions with the crude, a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Amorepacific

Curated by ChEMBL
LigandPNGBDBM50209568(4',7,8-trihydroxyisoflavone | 7,8,4'-trihydroxyiso...)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as decrease of superoxide generationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Amorepacific

Curated by ChEMBL
LigandPNGBDBM50209568(4',7,8-trihydroxyisoflavone | 7,8,4'-trihydroxyiso...)
Affinity DataIC50:  1.12E+4nMAssay Description:Inhibition of tyrosinase in mouse Melan-a cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease subunit beta(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50209568(4',7,8-trihydroxyisoflavone | 7,8,4'-trihydroxyiso...)
Affinity DataIC50:  1.40E+5nMAssay Description:Inhibition of Helicobacter pylori ATCC 43504 urease after 3 hrs pre-incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universidad De Santiago

LigandPNGBDBM50209568(4',7,8-trihydroxyisoflavone | 7,8,4'-trihydroxyiso...)
Affinity DataIC50: >1.50E+5nMpH: 8.0Assay Description:Approximately 2 µg of either COX-1 or COX-2 was added to buffer containing 100 µM AA, 0.1 M Tris-HCl buffer (pH 8.0), 5 mM EDTA, 2 mM phenol, and 1 µ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universidad De Santiago

LigandPNGBDBM50209568(4',7,8-trihydroxyisoflavone | 7,8,4'-trihydroxyiso...)
Affinity DataIC50: >1.50E+5nMpH: 8.0Assay Description:Approximately 2 µg of either COX-1 or COX-2 was added to buffer containing 100 µM AA, 0.1 M Tris-HCl buffer (pH 8.0), 5 mM EDTA, 2 mM phenol, and 1 µ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Amorepacific

Curated by ChEMBL
LigandPNGBDBM50209568(4',7,8-trihydroxyisoflavone | 7,8,4'-trihydroxyiso...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as decrease of uric acid generationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease subunit beta(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50209568(4',7,8-trihydroxyisoflavone | 7,8,4'-trihydroxyiso...)
Affinity DataIC50: >1.48E+6nMAssay Description:Inhibition of Helicobacter pylori ATCC 43504 urease in presence of 0.4 mM dithiothreitol after 3 hrs pre-incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease subunit beta(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50209568(4',7,8-trihydroxyisoflavone | 7,8,4'-trihydroxyiso...)
Affinity DataIC50: >1.48E+6nMAssay Description:Inhibition of Helicobacter pylori ATCC 43504 urease in presence of 0.4 mM 2-mercaptoethanol after 3 hrs pre-incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed