Compile Data Set for Download or QSAR
maximum 50k data
Found 4 of ic50 for monomerid = 50267581
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50267581((4Z)-4-[({[1-(3-Furyl)-2-oxo-1,2-dihydropyridin-4-...)
Affinity DataIC50:  60nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin) assessed as inhibition of retinoblastoma susceptibility gene product phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50267581((4Z)-4-[({[1-(3-Furyl)-2-oxo-1,2-dihydropyridin-4-...)
Affinity DataIC50:  370nMAssay Description:Inhibition of retinoblastoma susceptibility gene product phosphorylation in human MCF7 cells after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50267581((4Z)-4-[({[1-(3-Furyl)-2-oxo-1,2-dihydropyridin-4-...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin) assessed as inhibition of retinoblastoma susceptibility gene product phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50267581((4Z)-4-[({[1-(3-Furyl)-2-oxo-1,2-dihydropyridin-4-...)
Affinity DataIC50:  1.16E+4nMAssay Description:Inhibition of CDK1/Cyclin B1 (unknown origin) assessed as inhibition of retinoblastoma susceptibility gene product phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed