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Found 4 of ic50 for monomerid = 50272694
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272694(((3R,4R)-4-(2,3-dimethylphenoxy)-3,4-dihydro-1H-is...)
Affinity DataIC50:  27nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272694(((3R,4R)-4-(2,3-dimethylphenoxy)-3,4-dihydro-1H-is...)
Affinity DataIC50:  390nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272694(((3R,4R)-4-(2,3-dimethylphenoxy)-3,4-dihydro-1H-is...)
Affinity DataIC50:  880nMAssay Description:Inhibition of recombinant CYP32D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272694(((3R,4R)-4-(2,3-dimethylphenoxy)-3,4-dihydro-1H-is...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed