Compile Data Set for Download or QSAR
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Found 4 of ic50 for monomerid = 50274413
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50274413((+)-3-[[3-(5-Cyano-1H-indol-3-yl)propyl](cyclobuty...)
Affinity DataIC50:  24.1nMAssay Description:Inhibition of 5-HT transporter-mediated [3H]5HT uptake in human Jar cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50274413((+)-3-[[3-(5-Cyano-1H-indol-3-yl)propyl](cyclobuty...)
Affinity DataIC50:  24.1nMAssay Description:Inhibition of 5-HT transporter-mediated [3H]5HT uptake in human Jar cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50274413((+)-3-[[3-(5-Cyano-1H-indol-3-yl)propyl](cyclobuty...)
Affinity DataIC50:  195nMAssay Description:Activity at human cloned 5HT1A receptor expressed in CHO cells assessed as blockade of 5-HT-stimulated [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50274413((+)-3-[[3-(5-Cyano-1H-indol-3-yl)propyl](cyclobuty...)
Affinity DataIC50:  195nMAssay Description:Activity at human cloned 5HT1A receptor expressed in CHO cells assessed as blockade of 5-HT-stimulated [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed