Affinity DataIC50: 2.20nMAssay Description:Inhibition of CRTH2 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Antagonist activity at CRTH2 receptor in human whole blood assessed as inhibition of DK-PGD2-induced eosinophils shape changeMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Antagonist activity at CRTH2 in human eosinophil assessed as effect of cellular shape change by EOS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 expressed in HEK293 cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human recombinant CRTH2 receptor expressed in HEK293 cells assessed as inhibition of DK-PGD2-induced intracellular cAMP format...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human CRTH2 expressed in HEK293 cells assessed as inhibition of forskolin-induced increase intracellular [125I]cAMP level by s...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in HEK293-EBNA cells assessed as inhibition of forskolin-stimulated intracellular cAMP producti...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Displacement of [3H]PGD2 from human prostaglandin D2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]PGD2 from human prostaglandin D2 receptor in presence of human serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]PGD2 from prostaglandin D1 receptor in human platelet membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H]SQ-29548 from thromboxane receptor in human platelet membraneMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H]iloprost from human prostacyclin receptor expressed in human 293 cell membraneMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair