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Found 4 of ic50 for monomerid = 50305527
TargetCathepsin E(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50305527((4S)-4-[(1R)-1-hydroxy-2-({1-[3-(1-methylethyl)phe...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of cathepsin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50305527((4S)-4-[(1R)-1-hydroxy-2-({1-[3-(1-methylethyl)phe...)
Affinity DataIC50:  1nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50305527((4S)-4-[(1R)-1-hydroxy-2-({1-[3-(1-methylethyl)phe...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50305527((4S)-4-[(1R)-1-hydroxy-2-({1-[3-(1-methylethyl)phe...)
Affinity DataIC50:  20nMAssay Description:Inhibition of BACE1 expressed in APP-overexpressing CHO cellsMore data for this Ligand-Target Pair