BindingDB PrimarySearch

Found 2 of ic50 for monomerid = 50432652

E3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Amgen

Curated by ChEMBL

BDBM50432652(CHEMBL2347393 | US11407721, Example 79)

IC50: 610nMAssay Description:Inhibition of human recombinant GST-thrombin-MDM2 (1 to 188) expressed in Escherichia coli assessed as reduction of MDM2-p53 interaction incubated fo...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL MMDB PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

E3 ubiquitin-protein ligase Mdm2 [1-188](Homo sapiens (Human))
Amgen

US Patent

BDBM50432652(CHEMBL2347393 | US11407721, Example 79)

IC50: 1.00E+3nMAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

CHEMBL MMDB PC cid PC sid PDB Similars

Details US Patent PDB

3D Structure (crystal)