Compile Data Set for Download or QSAR
maximum 50k data
Found 3 of ic50 for monomerid = 50467633
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50467633(CHEMBL4291945)
Affinity DataIC50:  158nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged SYK expressed in baculovirus expression system using Biotin-AAAEEIYGEI as substrate after 60 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50467633(CHEMBL4291945)
Affinity DataIC50:  200nMAssay Description:Inhibition of recombinant human FLAG/His6-tagged Aurora-B (2 to 344 residues)/GST-tagged INCENP preincubated for 30 mins followed by 5FAM-PKA-tide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50467633(CHEMBL4291945)
Affinity DataIC50:  501nMAssay Description:Inhibition of SYK in human Ramos B cells assessed as reduction in anti-human IgM Fab2 fragment-induced ERK phosphorylation preincubated for 30 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed