Compile Data Set for Download or QSAR
maximum 50k data
Found 3 of ic50 for monomerid = 50538417
TargetUromodulin(Human)
Cadila Healthcare

US Patent
LigandPNGBDBM50538417(CHEMBL4643205 | US11236045, Example 55)
Affinity DataIC50:  27nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50538417(CHEMBL4643205 | US11236045, Example 55)
Affinity DataIC50:  34nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50538417(CHEMBL4643205 | US11236045, Example 55)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in TNF alpha level preincubated for 1 hr followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed