Found 2 of ic50 for monomerid = 50547968 TargetSerine/threonine-protein kinase/endoribonuclease IRE1(Homo sapiens (Human))
Paraza Pharma
Curated by ChEMBL
Paraza Pharma
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Competitive inhibition of IRE1alpha LKR domain (Q470 to L997 residues) (unknown origin) expressed in Sf9 insect cells using mini-XBP-1 stem-loop RNA ...More data for this Ligand-Target Pair
3D Structure (crystal)TargetSerine/threonine-protein kinase/endoribonuclease IRE1(Homo sapiens (Human))
Paraza Pharma
Curated by ChEMBL
Paraza Pharma
Curated by ChEMBL
Affinity DataIC50: 5.58E+3nMAssay Description:Inhibition of IRE1alpha (unknown origin) assessed as XBP-1 slicing luciferase activity incubated for 1 hr followed by stimulation with thapsigargin m...More data for this Ligand-Target Pair
