Affinity DataIC50: 26.2nMAssay Description:ATM: Recombinant, full length human FLAG-tagged ATM activity (Eurofins 14-933) was measured in an ELISA for p53 S15 phosphorylation, in a 384 well V-...More data for this Ligand-Target Pair
Affinity DataIC50: 520nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of ATR in human HT-29 cells assessed as reduction in CHK1 phosphorylation incubated for 4 hrsMore data for this Ligand-Target Pair