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Found 5 of ic50 for monomerid = 6356
LigandPNGBDBM6356(8-Cyclopentyl-2-(4-piperidin-1-yl-phenylamino)-8H-...)
Affinity DataIC50:  10nMpH: 7.4 T: 2°CAssay Description:The enzyme was assayed with substrate GST- retinoblastoma in the presence of 25 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
University Of Tours

Curated by ChEMBL
LigandPNGBDBM6356(8-Cyclopentyl-2-(4-piperidin-1-yl-phenylamino)-8H-...)
Affinity DataIC50:  245nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
University Of Tours

Curated by ChEMBL
LigandPNGBDBM6356(8-Cyclopentyl-2-(4-piperidin-1-yl-phenylamino)-8H-...)
Affinity DataIC50:  246nMAssay Description:The enzyme was assayed with substrate GST- retinoblastoma in the presence of 12 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM6356(8-Cyclopentyl-2-(4-piperidin-1-yl-phenylamino)-8H-...)
Affinity DataIC50:  570nMAssay Description:The enzyme was assayed with substrate GST- retinoblastoma in the presence of 12 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Pfizer

LigandPNGBDBM6356(8-Cyclopentyl-2-(4-piperidin-1-yl-phenylamino)-8H-...)
Affinity DataIC50:  660nMAssay Description:The enzyme was assayed with substrate GST- retinoblastoma in the presence of 12 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed