Compile Data Set for Download or QSAR
maximum 50k data
Found 3 of ic50 for monomerid = 8145
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM8145(N-(3,5-dichlorophenyl)-4-{pyrazolo[1,5-a]pyridazin...)
Affinity DataKi:  1nM IC50: <10nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
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TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM8145(N-(3,5-dichlorophenyl)-4-{pyrazolo[1,5-a]pyridazin...)
Affinity DataIC50:  316nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM8145(N-(3,5-dichlorophenyl)-4-{pyrazolo[1,5-a]pyridazin...)
Affinity DataIC50:  1.99E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed