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Found 5 of ic50 for monomerid = 8526
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Rattus norvegicus (Rat))
Astellas Pharma

US Patent
LigandPNGBDBM8526(CHEMBL1809170 | US8822447, 107 | US8822448, 184 | ...)
Affinity DataIC50:  40nMpH: 8.0Assay Description:The PDE9-inhibiting activity was measured by the following method. That is, to a buffer solution containing tris(hydroxymethyl)aminomethane-hydrochlo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKetohexokinase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM8526(CHEMBL1809170 | US8822447, 107 | US8822448, 184 | ...)
Affinity DataIC50:  40nMAssay Description:Inhibition of KHK-mediated conversion of D-fructose to fructose-1-phosphate after 60 mins by high throughput mass spectrometry analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKetohexokinase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM8526(CHEMBL1809170 | US8822447, 107 | US8822448, 184 | ...)
Affinity DataIC50:  40nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKetohexokinase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM8526(CHEMBL1809170 | US8822447, 107 | US8822448, 184 | ...)
Affinity DataIC50:  440nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKetohexokinase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM8526(CHEMBL1809170 | US8822447, 107 | US8822448, 184 | ...)
Affinity DataIC50:  440nMT: 2°CAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In DepthDetails US Patent