Compile Data Set for Download or QSAR
maximum 50k data
Found 4 of kd for monomerid = 333469
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM333469(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (6-ethoxy-7-...)
Affinity DataKd:  67nMAssay Description:Binding affinity to BRAF V600E mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM333469(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (6-ethoxy-7-...)
Affinity DataKd: <250nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM333469(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (6-ethoxy-7-...)
Affinity DataKd:  750nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM333469(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (6-ethoxy-7-...)
Affinity DataKd: >1.00E+3nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent