BindingDB PrimarySearch_ki

Found 29 of kd for monomerid = 50148603

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL

PNG

BDBM50148603(CHEMBL3770724)

Kd: 0.300nMAssay Description:Binding affinity to human partial length BRD4 BD2 expressed in bacterial expression system assessed as dissociation constant by BROMOscan assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL

PNG

BDBM50148603(CHEMBL3770724)

Kd: 3.40nMAssay Description:Binding affinity to BRD4 BD1 (unknown origin) assessed as dissociation constant by Discover X assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL

PNG

BDBM50148603(CHEMBL3770724)

Kd: 3.30E+3nMAssay Description:Inhibition of His-tagged BRD4 bromodomain 2 (E352 to E168 residues) (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL

PNG

BDBM50148603(CHEMBL3770724)

Kd: 3.30E+3nMAssay Description:Binding affinity to BRD4 BD1 (unknown origin) by isothermal titration calorimetric methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Bromodomain-containing protein 3(Homo sapiens (Human))
Gsk

Curated by ChEMBL

PNG

BDBM50148603(CHEMBL3770724)

Kd: 3.30E+3nMAssay Description:Binding affinity to BRD3 BD1 (unknown origin) by isothermal titration calorimetric methodMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details Article PubMed

Bromodomain-containing protein 2(Homo sapiens (Human))
Gsk

Curated by ChEMBL

PNG

BDBM50148603(CHEMBL3770724)

Kd: 3.30E+3nMAssay Description:Binding affinity to BRD2 BD1 (unknown origin) by isothermal titration calorimetric methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details Article PubMed

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL

PNG

BDBM50148603(CHEMBL3770724)

Kd: 3.40E+3nMAssay Description:Binding affinity to BRD4 BD1 (unknown origin) assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details PubMed PDB

3D Structure (crystal)

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL

PNG

BDBM50148603(CHEMBL3770724)

Kd: 3.40E+3nMAssay Description:Binding affinity to recombinant poly-His-tagged BRD4 bromodomain 1 (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL

PNG

BDBM50148603(CHEMBL3770724)

Kd: 3.40E+3nMAssay Description:Binding affinity to BRD4-BD1 (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details PubMed PDB

3D Structure (crystal)

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL

PNG

BDBM50148603(CHEMBL3770724)

Kd: 3.40E+3nMAssay Description:Inhibition of human 6x-His-tagged BRD4 bromodomain 1 expressed in Escherichia coliMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL

PNG

BDBM50148603(CHEMBL3770724)

Kd: 3.40E+3nMAssay Description:Binding affinity to BRD4 BD1 (unknown origin) by ITC analysisMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL

PNG

BDBM50148603(CHEMBL3770724)

Kd: 3.40E+3nMAssay Description:Binding affinity to BRD4 BD1 (unknown origin) by ITC methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Bromodomain-containing protein 3(Homo sapiens (Human))
Gsk

Curated by ChEMBL

PNG

BDBM50148603(CHEMBL3770724)

Kd: 3.70E+3nMAssay Description:Inhibition of poly-His tagged BRD3 bromodomain 2 (unknown origin) expressed in Escherichia coli BL21(DE3) by fluorescence anisotropy assayMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details Article PubMed

Bromodomain-containing protein 3(Homo sapiens (Human))
Gsk

Curated by ChEMBL

PNG

BDBM50148603(CHEMBL3770724)

Kd: 3.70E+3nMAssay Description:Inhibition of human 6x-His-tagged BRD3 bromodomain 1 expressed in Escherichia coliMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details Article PubMed

Bromodomain-containing protein 2(Homo sapiens (Human))
Gsk

Curated by ChEMBL

PNG

BDBM50148603(CHEMBL3770724)

Kd: 8.60E+3nMAssay Description:Inhibition of human 6x-His-tagged BRD2 bromodomain 1 expressed in Escherichia coliMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details Article PubMed

Bromodomain-containing protein 2(Homo sapiens (Human))
Gsk

Curated by ChEMBL

PNG

BDBM50148603(CHEMBL3770724)

Kd: 8.60E+3nMAssay Description:Binding affinity to recombinant poly-His-tagged BRD2 bromodomain 1 (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details Article PubMed

Bromodomain-containing protein 2(Homo sapiens (Human))
Gsk

Curated by ChEMBL

PNG

BDBM50148603(CHEMBL3770724)

Kd: 8.60E+3nMAssay Description:Inhibition of poly-His tagged BRD4 bromodomain 1 (unknown origin) expressed in Escherichia coli BL21(DE3) by fluorescence anisotropy assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details Article PubMed

CREB-binding protein(Homo sapiens (Human))
University of Texas Medical Branch

Curated by ChEMBL

PNG

BDBM50148603(CHEMBL3770724)

Kd: 3.30E+4nMAssay Description:Inhibition of poly-His tagged CREBBP (unknown origin) expressed in Escherichia coli BL21(DE3) by fluorescence anisotropy assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details Article PubMed

Bromodomain-containing protein 2(Homo sapiens (Human))
Gsk

Curated by ChEMBL

PNG

BDBM50148603(CHEMBL3770724)

Kd: >7.50E+4nMAssay Description:Inhibition of human 6x-His-tagged BRD2 bromodomain 2 expressed in Escherichia coliMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details Article PubMed

Bromodomain-containing protein 3(Homo sapiens (Human))
Gsk

Curated by ChEMBL

PNG

BDBM50148603(CHEMBL3770724)

Kd: >7.50E+4nMAssay Description:Inhibition of human 6x-His-tagged BRD3 bromodomain 2 expressed in Escherichia coliMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details Article PubMed

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL

PNG

BDBM50148603(CHEMBL3770724)

Kd: >7.50E+4nMAssay Description:Inhibition of human 6x-His-tagged BRD4 bromodomain 2 expressed in Escherichia coliMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL

PNG

BDBM50148603(CHEMBL3770724)

Kd: >3.00E+5nMAssay Description:Binding affinity to BRD4 BD2 (unknown origin) by isothermal titration calorimetric methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Bromodomain-containing protein 2(Homo sapiens (Human))
Gsk

Curated by ChEMBL

PNG

BDBM50148603(CHEMBL3770724)

Kd: >3.00E+5nMAssay Description:Binding affinity to recombinant poly-His-tagged BRD2 bromodomain 2 (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details Article PubMed

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL

PNG

BDBM50148603(CHEMBL3770724)

Kd: >3.00E+5nMAssay Description:Binding affinity to recombinant poly-His-tagged BRD4 bromodomain 2 (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL

PNG

BDBM50148603(CHEMBL3770724)

Kd: >3.00E+5nMAssay Description:Inhibition of poly-His tagged BRD4 bromodomain 2 (unknown origin) expressed in Escherichia coli BL21(DE3) by fluorescence anisotropy assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Bromodomain-containing protein 3(Homo sapiens (Human))
Gsk

Curated by ChEMBL

PNG

BDBM50148603(CHEMBL3770724)

Kd: >3.00E+5nMAssay Description:Inhibition of poly-His tagged BRD3 bromodomain 1 (unknown origin) expressed in Escherichia coli BL21(DE3) by fluorescence anisotropy assayMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details Article PubMed

Bromodomain-containing protein 2(Homo sapiens (Human))
Gsk

Curated by ChEMBL

PNG

BDBM50148603(CHEMBL3770724)

Kd: >3.00E+5nMAssay Description:Inhibition of poly-His tagged BRD2 bromodomain 2 (unknown origin) expressed in Escherichia coli BL21(DE3) by fluorescence anisotropy assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details Article PubMed

Bromodomain-containing protein 3(Homo sapiens (Human))
Gsk

Curated by ChEMBL

PNG

BDBM50148603(CHEMBL3770724)

Kd: >3.00E+5nMAssay Description:Binding affinity to BRD3 BD2 (unknown origin) by isothermal titration calorimetric methodMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details Article PubMed

Bromodomain-containing protein 2(Homo sapiens (Human))
Gsk

Curated by ChEMBL

PNG

BDBM50148603(CHEMBL3770724)

Kd: >3.00E+5nMAssay Description:Binding affinity to BRD2 BD2 (unknown origin) by isothermal titration calorimetric methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Purchase CHEMBL PC cid PC sid PDB Similars

Details Article PubMed

Filter my 29 hits

Targets 4▿
- Bromodomain-containing protein 4 14
- Bromodomain-containing protein 2 8
- Bromodomain-containing protein 3 6
- CREB-binding protein 1
Publications 8▿
- J Med Chem 60: 4533-4558 (2017) 7
- J Med Chem 61: 9316-9334 (2018) 6
- J Med Chem 63: 9020-9044 (2020) 6
- J Med Chem 59: 1492-500 (2016) 4
- J Med Chem 64: 10497-10511 (2021) 2
- J Med Chem 61: 4317-4334 (2018) 1
- J Med Chem 65: 5184-5211 (2022) 1
- Bioorg Med Chem 27: (2019) 1
Institutions 7▿
- University Of Minnesota 8
- University of Texas Medical Branch 7
- Gsk 6
- University Of Dundee 4
- University Of Strathclyde 1
- Monash University (Parkville Campus) 1
- Sichuan University 1
Affinity: 0.30 to 3.0E+5 nM▿
- Kd 29
- Affinity ≤ nM
Xtal structures: 1
Docked structures: 0
Catalog Cmpds: 1