Affinity DataKd: 0.350nMAssay Description:Binding constant for EGFR(L747-T751del,Sins) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 0.350nMAssay Description:Binding constant for EGFR(L747-T751del,Sins) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 0.350nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 0.470nMAssay Description:Binding constant for EGFR(L747-S752del, P753S) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 0.470nMAssay Description:Binding constant for EGFR(L747-S752del, P753S) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 0.470nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 0.480nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 0.480nMAssay Description:Binding constant for EGFR(E746-A750del) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 0.480nMAssay Description:Binding constant for EGFR(E746-A750del) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 0.520nMAssay Description:Binding constant for EGFR(L747-E749del, A750P) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 0.520nMAssay Description:Binding constant for EGFR(G719S) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 0.520nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 0.520nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 0.520nMAssay Description:Binding constant for EGFR(G719S) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 0.520nMAssay Description:Binding constant for EGFR(L747-E749del, A750P) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 0.670nMAssay Description:Binding constant for EGFR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 0.670nMAssay Description:Binding constant for EGFR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 0.670nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 0.700nMAssay Description:Binding affinity to T7-tagged EGFR (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hrMore data for this Ligand-Target Pair
Affinity DataKd: 0.700nMAssay Description:Binding affinity to wild-type human partial length EGFR (R669 to V1011 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
Affinity DataKd: 0.850nMAssay Description:Binding constant for EGFR(G719C) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 0.850nMAssay Description:Binding constant for EGFR(G719C) kinase domainMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [G719C](Homo sapiens (Human))
Ambit Biosciences
Curated by PubChem BioAssay
Ambit Biosciences
Curated by PubChem BioAssay
Affinity DataKd: 0.850nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 0.970nMAssay Description:Binding constant for EGFR(L858R) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 0.970nMAssay Description:Binding constant for EGFR(L858R) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1nMAssay Description:Binding affinity to human EGFR after 1 hr by qPCR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 1.20nMAssay Description:Binding constant for EGFR(L861Q) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.20nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 1.20nMAssay Description:Binding constant for EGFR(L861Q) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.40nMAssay Description:Average Binding Constant for EGFR; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
Affinity DataKd: 1.60nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 1.60nMAssay Description:Binding constant for EGFR(S752-I759del) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.60nMAssay Description:Binding constant for EGFR(S752-I759del) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 3.10nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 3.10nMAssay Description:Binding affinity to human GAK fused to T7 bacteriophage after 1 hr by qPCR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 3.10nMAssay Description:Binding affinity to T7-tagged GAK (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hrMore data for this Ligand-Target Pair
Affinity DataKd: 3.10nMAssay Description:Binding affinity to GAK (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 3.10nMAssay Description:Binding affinity to GAK (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 3.10nMAssay Description:Binding affinity to GAK (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 3.10nMAssay Description:Binding affinity to wild-type human partial length GAK (G13 to Y338 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
Affinity DataKd: 3.10nMAssay Description:Binding affinity to DNA-tagged human GAK expressed in Escherichia coli BL21 using immobilised ligand incubated for 1 hr by quantitative PCRMore data for this Ligand-Target Pair
Affinity DataKd: 3.10nMAssay Description:Binding constant for GAK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 3.10nMAssay Description:Binding constant for GAK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 3.10nMAssay Description:Binding affinity to GAK (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Affinity DataKd: 19nMAssay Description:Binding constant for LOK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 19nMAssay Description:Binding constant for LOK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 21nMAssay Description:Binding affinity to GAK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 19(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 25nMAssay Description:Binding constant for YSK4 kinase domainMore data for this Ligand-Target Pair
TargetSTE20-like serine/threonine-protein kinase(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 26nMAssay Description:Binding constant for SLK kinase domainMore data for this Ligand-Target Pair
TargetSTE20-like serine/threonine-protein kinase(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 26nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair