Compile Data Set for Download or QSAR
maximum 50k data
Found 13 of ki for monomerid = 370120
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM370120(6-chloro-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]...)
Affinity DataKi:  0.160nMAssay Description:The purpose of the CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a flu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM370120(6-chloro-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]...)
Affinity DataKi:  0.160nMAssay Description:The mobility shift assay electrophoretically separates the fluorescently labeled peptides (substrate and phosphorylated product) following the kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM370120(6-chloro-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]...)
Affinity DataKi:  0.160nMAssay Description:The purpose of the CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a flu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM370120(6-chloro-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of CDK2/cyclin E1 (unknown origin) assessed as reduction in substrate peptide phosphorylation using DYRKtide peptide as substrate preincub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM370120(6-chloro-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]...)
Affinity DataKi:  0.25nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM370120(6-chloro-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]...)
Affinity DataKi:  0.25nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM370120(6-chloro-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]...)
Affinity DataKi:  0.25nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM370120(6-chloro-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]...)
Affinity DataKi:  0.370nMAssay Description:Inhibition of CDK6/cyclin D1 (unknown origin) assessed as reduction in substrate peptide phosphorylation using DYRKtide peptide as substrate preincub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM370120(6-chloro-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]...)
Affinity DataKi:  0.450nMAssay Description:Inhibition of CDK4/cyclin D1 (unknown origin) assessed as reduction in substrate peptide phosphorylation using DYRKtide peptide as substrate preincub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM370120(6-chloro-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]...)
Affinity DataKi:  1.12nMAssay Description:The purpose CDK4/Cyclin D3 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitors by us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM370120(6-chloro-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]...)
Affinity DataKi:  1.12nMAssay Description:The purpose CDK4/Cyclin D3 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitors by us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM370120(6-chloro-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]...)
Affinity DataKi:  1.12nMAssay Description:The purpose CDK4/Cyclin D3 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitors by us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM370120(6-chloro-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]...)
Affinity DataKi:  37nMAssay Description:Inhibition of CDK9/Cyclin-T1 (unknown origin) assessed as reduction in substrate peptide phosphorylation using DYRKtide peptide as substrate preincub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed