Compile Data Set for Download or QSAR
maximum 50k data
Found 15 of ki for monomerid = 50308131
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

US Patent
LigandPNGBDBM50308131(4-{1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)benzyl]...)
Affinity DataKi:  0.5nM ΔG°:  -53.1kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

US Patent
LigandPNGBDBM50308131(4-{1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)benzyl]...)
Affinity DataKi:  0.560nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK293-EBNA cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50308131(4-{1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)benzyl]...)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]PGE2 from rat EP4 receptor expressed in HEK293-EBNA cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

US Patent
LigandPNGBDBM50308131(4-{1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)benzyl]...)
Affinity DataKi:  0.970nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK293-EBNA cells by scintillation counting in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(RAT)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50308131(4-{1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)benzyl]...)
Affinity DataKi:  3.30E+3nMAssay Description:Displacement of [3H]PGE2 from rat EP3 receptor expressed in HEK293-EBNA cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50308131(4-{1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)benzyl]...)
Affinity DataKi: >3.90E+3nMAssay Description:Displacement of [3H]PGD2 from human DP1 receptor expressed in HEK293-EBNA cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50308131(4-{1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)benzyl]...)
Affinity DataKi: >5.60E+3nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in HEK293-EBNA cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50308131(4-{1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)benzyl]...)
Affinity DataKi:  5.90E+3nMAssay Description:Displacement of [3H]PGE2 from human EP2 receptor expressed in HEK293-EBNA cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50308131(4-{1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)benzyl]...)
Affinity DataKi: >6.80E+3nMAssay Description:Displacement of [3H]SQ29548 from human TP receptor expressed in HEK293-EBNA cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50308131(4-{1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)benzyl]...)
Affinity DataKi:  7.20E+3nMAssay Description:Displacement of [3H]PGE2 from rat EP2 receptor expressed in HEK293-EBNA cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50308131(4-{1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)benzyl]...)
Affinity DataKi: >7.90E+3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor expressed in HEK293-EBNA cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50308131(4-{1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)benzyl]...)
Affinity DataKi: >2.10E+4nMAssay Description:Displacement of [3H]PGD2 from human DP2 receptor expressed in HEK293-EBNA cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50308131(4-{1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)benzyl]...)
Affinity DataKi: >2.20E+4nMAssay Description:Displacement of [3H]iloprost from human IP receptor expressed in HEK293-EBNA cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50308131(4-{1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)benzyl]...)
Affinity DataKi: >2.40E+4nMAssay Description:Displacement of [3H]PGF2alpha from human FP receptor expressed in HEK293-EBNA cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50308131(4-{1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)benzyl]...)
Affinity DataKi: >2.90E+4nMAssay Description:Displacement of [3H]PGE2 from rat EP1 receptor expressed in HEK293-EBNA cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed