Report error Found 44 Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50005118'
Affinity DataKi: 1.10nMAssay Description:Compound was evaluated for the inhibition constant against dopamine receptor D2 in ratMore data for this Ligand-Target Pair
Affinity DataKd: 1.10nMAssay Description:Affinity constant of compound was evaluated in rat striatum tissue preparation.More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Competitive binding assay against Dopamine receptor D2 in rat striatal membranes and [125I]-IBF radioligandMore data for this Ligand-Target Pair
Affinity DataKd: 1.20nMAssay Description:Binding affinity to D2 receptor in rat brain striatal homogenates after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of [3H]raclopride binding to rat striatal dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of 0.1 nM of [125I]- (S)-N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2-methoxy-benzamide binding in striatal homogenates of rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of [3H]spiperone binding to rat striatal membrane Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Antagonist activity at C-terminal RLuc8-fused D2 long receptor (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tag...More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:In vitro binding affinity against dopamine receptor D2 in rat striata; value ranges from 1.8-3.0 nMMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Antagonist activity at C-terminal RLuc8-fused D2 long receptor (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tag...More data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]raclopride from dopamine D2 receptor in Sprague-Dawley rat striatal membranes after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:In vitro binding affinity for Dopamine D2 receptor of rat using [3H]YM-09151 as radioligandMore data for this Ligand-Target Pair
Affinity DataKd: 7.10nMAssay Description:Affinity constant of compound was evaluated in human brainMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:In vivo inhibitory activity against dopamine (D2) receptor in rat caudate-putamen tissueMore data for this Ligand-Target Pair
Affinity DataKi: 8.30nMAssay Description:Compound was evaluated for binding affinity towards dopamine receptor D2 in striatal membranes, using [3H]- spiperone as radioligand in the presence ...More data for this Ligand-Target Pair
Affinity DataKi: 9.5nMAssay Description:Compound was evaluated for binding affinity towards DA D-2 receptor using radioligand [3H]SPIMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D2 receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Binding affinity to dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of [3H](S)-sulpiride binding in striatal homogenates of rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [3H]spiperone from dopamine D2long receptor in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Displacement of [3H]spiperone from dopamine D2short receptor in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of [3H]spiperone binding to rat striatal dopamine receptor D2 was determined in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:The affinity for the Dopamine receptor D2 was assessed by the inhibition of [3H]-spiperone binding in rat striatal membranes in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibitory concentration required for displacing radioligand [3H]SPI from DA D-2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Displacement of [3H]- spiperone from dopamine receptor D2 of striatal membranes without sodium chlorideMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Antagonist activity at D2 long receptor (unknown origin) transfected in human HEK293T cells assessed as increase in cAMP accumulation incubated for 2...More data for this Ligand-Target Pair
Affinity DataIC50: 104nMAssay Description:Antagonist activity at D2 long receptor (unknown origin) transfected in human HEK293T cells assessed as increase in cAMP accumulation incubated for 2...More data for this Ligand-Target Pair
