Affinity DataKi: 6nM ΔG°: -48.8kJ/mole IC50: 32nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
Affinity DataKi: 9nM ΔG°: -47.8kJ/mole IC50: 51nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
Affinity DataKi: 11nM ΔG°: -47.3kJ/mole IC50: 60nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
Affinity DataKi: 13nM ΔG°: -46.8kJ/mole IC50: 73nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
Affinity DataKi: 19nM ΔG°: -45.8kJ/mole IC50: 107nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
Affinity DataKi: 20nM ΔG°: -45.7kJ/mole IC50: 112nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
Affinity DataKi: 26nM ΔG°: -45.0kJ/mole IC50: 146nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
Affinity DataKi: 28nM ΔG°: -44.8kJ/mole IC50: 154nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
Affinity DataKi: 39nM IC50: 202nMpH: 7.8Assay Description:Inhibition activity of HCV NS3-NS4A.More data for this Ligand-Target Pair
Affinity DataKi: 40nM ΔG°: -43.9kJ/mole IC50: 222nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
Affinity DataKi: 41nM ΔG°: -43.9kJ/mole IC50: 231nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
Affinity DataKi: 44nM ΔG°: -43.7kJ/mole IC50: 245nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
Affinity DataKi: 46nM ΔG°: -43.6kJ/mole IC50: 255nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
Affinity DataKi: 49nM ΔG°: -43.4kJ/mole IC50: 271nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
Affinity DataKi: 53nM ΔG°: -43.2kJ/mole IC50: 297nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
Affinity DataKi: 58nM ΔG°: -43.0kJ/mole IC50: 325nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
Affinity DataKi: 81nM ΔG°: -42.1kJ/mole IC50: 454nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
Affinity DataKi: 104nM ΔG°: -41.5kJ/mole IC50: 580nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
Affinity DataKi: 111nM ΔG°: -41.3kJ/mole IC50: 619nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
Affinity DataKi: 160nM ΔG°: -40.3kJ/mole IC50: 891nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
Affinity DataKi: 2.07E+3nM ΔG°: -33.7kJ/mole IC50: 1.16E+4nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
Affinity DataKi: 4.60E+3nM ΔG°: -31.7kJ/mole IC50: 2.57E+4nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
TargetGenome polyprotein [1973-2419](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
TBA
US Patent
TBA
US Patent
Affinity DataIC50: 0.000790nMT: 2°CAssay Description:Solutions of the tested compounds in DMEM medium {DMEM) 1x; Source: Cellgro; Catalogue: 10-013-CV} were prepared immediately before use. Eleven seria...More data for this Ligand-Target Pair
TargetGenome polyprotein [1973-2419](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
TBA
US Patent
TBA
US Patent
Affinity DataIC50: 0.00180nMT: 2°CAssay Description:Solutions of the tested compounds in DMEM medium {DMEM) 1x; Source: Cellgro; Catalogue: 10-013-CV} were prepared immediately before use. Eleven seria...More data for this Ligand-Target Pair
TargetGenome polyprotein [1973-2419](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
TBA
US Patent
TBA
US Patent
Affinity DataIC50: 0.00200nMT: 2°CAssay Description:Solutions of the tested compounds in DMEM medium {DMEM) 1x; Source: Cellgro; Catalogue: 10-013-CV} were prepared immediately before use. Eleven seria...More data for this Ligand-Target Pair
TargetGenome polyprotein [1973-2419](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
TBA
US Patent
TBA
US Patent
Affinity DataIC50: 0.00310nMT: 2°CAssay Description:Solutions of the tested compounds in DMEM medium {DMEM) 1x; Source: Cellgro; Catalogue: 10-013-CV} were prepared immediately before use. Eleven seria...More data for this Ligand-Target Pair
TargetGenome polyprotein [1973-2419](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
TBA
US Patent
TBA
US Patent
Affinity DataIC50: 0.00320nMT: 2°CAssay Description:Solutions of the tested compounds in DMEM medium {DMEM) 1x; Source: Cellgro; Catalogue: 10-013-CV} were prepared immediately before use. Eleven seria...More data for this Ligand-Target Pair
TargetGenome polyprotein [1973-2419](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
TBA
US Patent
TBA
US Patent
Affinity DataIC50: 0.00340nMT: 2°CAssay Description:Solutions of the tested compounds in DMEM medium {DMEM) 1x; Source: Cellgro; Catalogue: 10-013-CV} were prepared immediately before use. Eleven seria...More data for this Ligand-Target Pair
TargetGenome polyprotein [1973-2419](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
TBA
US Patent
TBA
US Patent
Affinity DataIC50: 0.00360nMT: 2°CAssay Description:Solutions of the tested compounds in DMEM medium {DMEM) 1x; Source: Cellgro; Catalogue: 10-013-CV} were prepared immediately before use. Eleven seria...More data for this Ligand-Target Pair
TargetGenome polyprotein [1973-2419](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
TBA
US Patent
TBA
US Patent
Affinity DataIC50: 0.00400nMT: 2°CAssay Description:Solutions of the tested compounds in DMEM medium {DMEM) 1x; Source: Cellgro; Catalogue: 10-013-CV} were prepared immediately before use. Eleven seria...More data for this Ligand-Target Pair
TargetGenome polyprotein [1973-2419](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
TBA
US Patent
TBA
US Patent
Affinity DataIC50: 0.00460nMT: 2°CAssay Description:Solutions of the tested compounds in DMEM medium {DMEM) 1x; Source: Cellgro; Catalogue: 10-013-CV} were prepared immediately before use. Eleven seria...More data for this Ligand-Target Pair
TargetGenome polyprotein [1973-2419](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
TBA
US Patent
TBA
US Patent
Affinity DataIC50: 0.00480nMT: 2°CAssay Description:Solutions of the tested compounds in DMEM medium {DMEM) 1x; Source: Cellgro; Catalogue: 10-013-CV} were prepared immediately before use. Eleven seria...More data for this Ligand-Target Pair
TargetGenome polyprotein [1973-2419](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
TBA
US Patent
TBA
US Patent
Affinity DataIC50: 0.00540nMT: 2°CAssay Description:Solutions of the tested compounds in DMEM medium {DMEM) 1x; Source: Cellgro; Catalogue: 10-013-CV} were prepared immediately before use. Eleven seria...More data for this Ligand-Target Pair
TargetGenome polyprotein [1973-2419](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
TBA
US Patent
TBA
US Patent
Affinity DataIC50: 0.00820nMT: 2°CAssay Description:Solutions of the tested compounds in DMEM medium {DMEM) 1x; Source: Cellgro; Catalogue: 10-013-CV} were prepared immediately before use. Eleven seria...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease R155K mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease R155K mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease R155K mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease R155K mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease R155K mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease D168Y mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease R155K mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome
Curated by ChEMBL
Irbm, Mrl Rome
Curated by ChEMBL
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease R155K mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease D168Y mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease R155K mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease D168Y mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease R155K mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease A156T mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease D168Y mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease R155K mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair