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TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University of Queensland

LigandPNGBDBM24732((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  6nM ΔG°:  -48.8kJ/mole IC50:  32nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University of Queensland

LigandPNGBDBM24731((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  9nM ΔG°:  -47.8kJ/mole IC50:  51nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University of Queensland

LigandPNGBDBM24734((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  11nM ΔG°:  -47.3kJ/mole IC50:  60nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University of Queensland

LigandPNGBDBM24746((2S)-6-amino-N-[(1S)-4-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  13nM ΔG°:  -46.8kJ/mole IC50:  73nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University of Queensland

LigandPNGBDBM24739((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  19nM ΔG°:  -45.8kJ/mole IC50:  107nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University of Queensland

LigandPNGBDBM24733((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  20nM ΔG°:  -45.7kJ/mole IC50:  112nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University of Queensland

LigandPNGBDBM24735((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  26nM ΔG°:  -45.0kJ/mole IC50:  146nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University of Queensland

LigandPNGBDBM24741((2S)-6-amino-N-[(2S)-5-carbamimidamido-1-oxopentan...)
Affinity DataKi:  28nM ΔG°:  -44.8kJ/mole IC50:  154nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1711](Hepatitis C virus (HCV))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM98165(US8486989, IA)
Affinity DataKi:  39nM IC50:  202nMpH: 7.8Assay Description:Inhibition activity of HCV NS3-NS4A.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University of Queensland

LigandPNGBDBM24736(Capped tripeptide aldehyde inhibitor, 24 | benzyl ...)
Affinity DataKi:  40nM ΔG°:  -43.9kJ/mole IC50:  222nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University of Queensland

LigandPNGBDBM24728((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  41nM ΔG°:  -43.9kJ/mole IC50:  231nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University of Queensland

LigandPNGBDBM24744((2S)-N-[(1S)-5-amino-1-{[(2S)-5-carbamimidamido-1-...)
Affinity DataKi:  44nM ΔG°:  -43.7kJ/mole IC50:  245nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University of Queensland

LigandPNGBDBM24742((2S)-6-amino-2-[(2S)-5-amino-2-(1-phenylacetamido)...)
Affinity DataKi:  46nM ΔG°:  -43.6kJ/mole IC50:  255nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University of Queensland

LigandPNGBDBM24737((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  49nM ΔG°:  -43.4kJ/mole IC50:  271nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University of Queensland

LigandPNGBDBM24748((2S)-2-[(2S)-6-amino-2-(1-phenylacetamido)hexanami...)
Affinity DataKi:  53nM ΔG°:  -43.2kJ/mole IC50:  297nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University of Queensland

LigandPNGBDBM24745((2S)-6-amino-N-[(1S)-4-carbamimidamido-1-{[(2S)-5-...)
Affinity DataKi:  58nM ΔG°:  -43.0kJ/mole IC50:  325nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University of Queensland

LigandPNGBDBM24738((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  81nM ΔG°:  -42.1kJ/mole IC50:  454nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University of Queensland

LigandPNGBDBM24730((2S)-6-amino-2-[(2S)-6-amino-2-[(2E)-3-phenylprop-...)
Affinity DataKi:  104nM ΔG°:  -41.5kJ/mole IC50:  580nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University of Queensland

LigandPNGBDBM24743((2S)-6-amino-N-[(2S)-5-carbamimidamido-1-oxopentan...)
Affinity DataKi:  111nM ΔG°:  -41.3kJ/mole IC50:  619nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University of Queensland

LigandPNGBDBM24740((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-5-carbamimid...)
Affinity DataKi:  160nM ΔG°:  -40.3kJ/mole IC50:  891nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University of Queensland

LigandPNGBDBM24747((2S)-6-amino-N-[(1S)-1-{[(2S)-5-carbamimidamido-1-...)
Affinity DataKi:  2.07E+3nM ΔG°:  -33.7kJ/mole IC50:  1.16E+4nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University of Queensland

LigandPNGBDBM24749((2S)-6-amino-N-[(1S)-5-amino-1-{[(2S)-1-(1H-indol-...)
Affinity DataKi:  4.60E+3nM ΔG°:  -31.7kJ/mole IC50:  2.57E+4nMpH: 9.5 T: 2°CAssay Description:Inhibition of WNV protease activity was measured using recombinant WNV protease, which first incubated with inhibitor in 96-well plates. Catalysis wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1973-2419](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
TBA

US Patent
LigandPNGBDBM244109(US9428491, 1.2: 2HCl)
Affinity DataIC50:  0.000790nMT: 2°CAssay Description:Solutions of the tested compounds in DMEM medium {DMEM) 1x; Source: Cellgro; Catalogue: 10-013-CV} were prepared immediately before use. Eleven seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1973-2419](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
TBA

US Patent
LigandPNGBDBM244111(US9428491, 1.4: 2HCl)
Affinity DataIC50:  0.00180nMT: 2°CAssay Description:Solutions of the tested compounds in DMEM medium {DMEM) 1x; Source: Cellgro; Catalogue: 10-013-CV} were prepared immediately before use. Eleven seria...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein [1973-2419](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
TBA

US Patent
LigandPNGBDBM244105(US9428491, 1.10: 2HCl)
Affinity DataIC50:  0.00200nMT: 2°CAssay Description:Solutions of the tested compounds in DMEM medium {DMEM) 1x; Source: Cellgro; Catalogue: 10-013-CV} were prepared immediately before use. Eleven seria...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein [1973-2419](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
TBA

US Patent
LigandPNGBDBM244106(US9428491, 1.1 | US9428491, 1.1: 2HCl | US9428491,...)
Affinity DataIC50:  0.00310nMT: 2°CAssay Description:Solutions of the tested compounds in DMEM medium {DMEM) 1x; Source: Cellgro; Catalogue: 10-013-CV} were prepared immediately before use. Eleven seria...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein [1973-2419](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
TBA

US Patent
LigandPNGBDBM244114(US9428491, 1.9: 2HCl)
Affinity DataIC50:  0.00320nMT: 2°CAssay Description:Solutions of the tested compounds in DMEM medium {DMEM) 1x; Source: Cellgro; Catalogue: 10-013-CV} were prepared immediately before use. Eleven seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1973-2419](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
TBA

US Patent
LigandPNGBDBM244106(US9428491, 1.1 | US9428491, 1.1: 2HCl | US9428491,...)
Affinity DataIC50:  0.00340nMT: 2°CAssay Description:Solutions of the tested compounds in DMEM medium {DMEM) 1x; Source: Cellgro; Catalogue: 10-013-CV} were prepared immediately before use. Eleven seria...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein [1973-2419](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
TBA

US Patent
LigandPNGBDBM244104(US9428491, 1.7: 2HCl)
Affinity DataIC50:  0.00360nMT: 2°CAssay Description:Solutions of the tested compounds in DMEM medium {DMEM) 1x; Source: Cellgro; Catalogue: 10-013-CV} were prepared immediately before use. Eleven seria...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein [1973-2419](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
TBA

US Patent
LigandPNGBDBM244106(US9428491, 1.1 | US9428491, 1.1: 2HCl | US9428491,...)
Affinity DataIC50:  0.00400nMT: 2°CAssay Description:Solutions of the tested compounds in DMEM medium {DMEM) 1x; Source: Cellgro; Catalogue: 10-013-CV} were prepared immediately before use. Eleven seria...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein [1973-2419](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
TBA

US Patent
LigandPNGBDBM244108(US9428491, 1.6: 2HCl)
Affinity DataIC50:  0.00460nMT: 2°CAssay Description:Solutions of the tested compounds in DMEM medium {DMEM) 1x; Source: Cellgro; Catalogue: 10-013-CV} were prepared immediately before use. Eleven seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1973-2419](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
TBA

US Patent
LigandPNGBDBM244113(US9428491, 1.8: 2HCl)
Affinity DataIC50:  0.00480nMT: 2°CAssay Description:Solutions of the tested compounds in DMEM medium {DMEM) 1x; Source: Cellgro; Catalogue: 10-013-CV} were prepared immediately before use. Eleven seria...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein [1973-2419](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
TBA

US Patent
LigandPNGBDBM244110(US9428491, 1.3: 2HCl)
Affinity DataIC50:  0.00540nMT: 2°CAssay Description:Solutions of the tested compounds in DMEM medium {DMEM) 1x; Source: Cellgro; Catalogue: 10-013-CV} were prepared immediately before use. Eleven seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1973-2419](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
TBA

US Patent
LigandPNGBDBM244112(US9428491, 1.5: 2HCl)
Affinity DataIC50:  0.00820nMT: 2°CAssay Description:Solutions of the tested compounds in DMEM medium {DMEM) 1x; Source: Cellgro; Catalogue: 10-013-CV} were prepared immediately before use. Eleven seria...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM50495931(CHEMBL3348818)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease R155K mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C Virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM50495927(CHEMBL3348817)
Affinity DataIC50:  0.0200nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease R155K mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C Virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM50495935(CHEMBL3120475)
Affinity DataIC50:  0.0200nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease R155K mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C Virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM50495928(CHEMBL3349199)
Affinity DataIC50:  0.0200nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease R155K mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C Virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM50495924(CHEMBL3120477)
Affinity DataIC50:  0.0300nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease R155K mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C Virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM50495931(CHEMBL3348818)
Affinity DataIC50:  0.0400nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease D168Y mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C Virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM50495936(CHEMBL3120492)
Affinity DataIC50:  0.0500nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease R155K mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50461540(CHEMBL4226033)
Affinity DataIC50:  0.0500nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C Virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM50495943(CHEMBL3349202)
Affinity DataIC50:  0.0500nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease R155K mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C Virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM50495928(CHEMBL3349199)
Affinity DataIC50:  0.0500nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease D168Y mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C Virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM50495929(CHEMBL3120493)
Affinity DataIC50:  0.0600nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease R155K mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C Virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM50495927(CHEMBL3348817)
Affinity DataIC50:  0.0600nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease D168Y mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C Virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM50485492(Grazoprevir | Grazoprevir monohydrate | MK-5172 | ...)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease R155K mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C Virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM50495928(CHEMBL3349199)
Affinity DataIC50:  0.0800nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease A156T mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C Virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM50495935(CHEMBL3120475)
Affinity DataIC50:  0.0900nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease D168Y mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C Virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM50495942(CHEMBL3120488)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease R155K mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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