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Found 60 with Last Name = 'george zhang' and Initial = 'y'
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193999(2-(3H-imidazo[4,5-c]pyridin-3-yl)-N-((S)-1-phenyle...)
Affinity DataIC50:  4nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194011(2-(3H-imidazo[4,5-c]pyridin-3-yl)-N4,N4-dimethyl-N...)
Affinity DataIC50:  7nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193989(CHEMBL221976 | N-((S)-1-(4-fluorophenyl)ethyl)-2-(...)
Affinity DataIC50:  8nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  11nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194009(6-(3,4-dimethoxyphenyl)-2-(3H-imidazo[4,5-c]pyridi...)
Affinity DataIC50:  12nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  13nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193990(6-(furan-3-yl)-2-(3H-imidazo[4,5-c]pyridin-3-yl)-N...)
Affinity DataIC50:  16nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194015(3-(4-(2-chlorophenoxy)-6-(4-methylpiperazin-1-yl)p...)
Affinity DataIC50:  17nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193994(4-(2-(3H-imidazo[4,5-c]pyridin-3-yl)-6-((S)-1-phen...)
Affinity DataIC50:  18nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194011(2-(3H-imidazo[4,5-c]pyridin-3-yl)-N4,N4-dimethyl-N...)
Affinity DataIC50:  19nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193991(2-(3H-imidazo[4,5-c]pyridin-3-yl)-6-(4-methylpiper...)
Affinity DataIC50:  19nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194010(6-(4-(dimethylamino)phenyl)-2-(3H-imidazo[4,5-c]py...)
Affinity DataIC50:  20nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193999(2-(3H-imidazo[4,5-c]pyridin-3-yl)-N-((S)-1-phenyle...)
Affinity DataIC50:  21nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194015(3-(4-(2-chlorophenoxy)-6-(4-methylpiperazin-1-yl)p...)
Affinity DataIC50:  27nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194005(CHEMBL221378 | N-((S)-1-(4-fluorophenyl)ethyl)-6-(...)
Affinity DataIC50:  28nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194008(3-(4-(furan-3-yl)-6-((S)-1-phenylethylamino)pyrimi...)
Affinity DataIC50:  29nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194008(3-(4-(furan-3-yl)-6-((S)-1-phenylethylamino)pyrimi...)
Affinity DataIC50:  31nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132420(3-((1H-pyrrol-2-yl)methylene)-5-(pyridin-3-yl)indo...)
Affinity DataIC50:  38nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193994(4-(2-(3H-imidazo[4,5-c]pyridin-3-yl)-6-((S)-1-phen...)
Affinity DataIC50:  42nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193993(3-(4-((S)-1-methoxypropan-2-ylamino)pyrimidin-2-yl...)
Affinity DataIC50:  45nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193987(4-(3H-imidazo[4,5-c]pyridin-3-yl)-N-((R)-1-phenyle...)
Affinity DataIC50:  49nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194009(6-(3,4-dimethoxyphenyl)-2-(3H-imidazo[4,5-c]pyridi...)
Affinity DataIC50:  49nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194004(CHEMBL218746 | N-((S)-1-(4-chlorophenyl)ethyl)-2-(...)
Affinity DataIC50:  51nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193996(2-(1H-imidazo[4,5-c]pyridin-1-yl)-N-((S)-1-phenyle...)
Affinity DataIC50:  51nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193997(6-(furan-3-yl)-2-(3H-imidazo[4,5-c]pyridin-3-yl)-N...)
Affinity DataIC50:  51nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194000(3-(2-(3H-imidazo[4,5-c]pyridin-3-yl)-6-((S)-1-phen...)
Affinity DataIC50:  56nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194013((R)-1-(2-(3H-imidazo[4,5-c]pyridin-3-yl)-6-((S)-1-...)
Affinity DataIC50:  59nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193990(6-(furan-3-yl)-2-(3H-imidazo[4,5-c]pyridin-3-yl)-N...)
Affinity DataIC50:  60nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193991(2-(3H-imidazo[4,5-c]pyridin-3-yl)-6-(4-methylpiper...)
Affinity DataIC50:  61nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194010(6-(4-(dimethylamino)phenyl)-2-(3H-imidazo[4,5-c]py...)
Affinity DataIC50:  62nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194007(3-(4-(2,6-difluorophenoxy)-6-(4-methylpiperazin-1-...)
Affinity DataIC50:  68nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194014(2-(3H-imidazo[4,5-c]pyridin-3-yl)-6-(1-methyl-1H-p...)
Affinity DataIC50:  77nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194005(CHEMBL221378 | N-((S)-1-(4-fluorophenyl)ethyl)-6-(...)
Affinity DataIC50:  83nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193989(CHEMBL221976 | N-((S)-1-(4-fluorophenyl)ethyl)-2-(...)
Affinity DataIC50:  92nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194002(CHEMBL376885 | N-(2-chlorophenyl)-2-(3H-imidazo[4,...)
Affinity DataIC50:  113nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194007(3-(4-(2,6-difluorophenoxy)-6-(4-methylpiperazin-1-...)
Affinity DataIC50:  120nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193993(3-(4-((S)-1-methoxypropan-2-ylamino)pyrimidin-2-yl...)
Affinity DataIC50:  124nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194002(CHEMBL376885 | N-(2-chlorophenyl)-2-(3H-imidazo[4,...)
Affinity DataIC50:  131nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193997(6-(furan-3-yl)-2-(3H-imidazo[4,5-c]pyridin-3-yl)-N...)
Affinity DataIC50:  141nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193987(4-(3H-imidazo[4,5-c]pyridin-3-yl)-N-((R)-1-phenyle...)
Affinity DataIC50:  145nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194003(2-(3H-imidazo[4,5-c]pyridin-3-yl)-N-methyl-N-((S)-...)
Affinity DataIC50:  153nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193997(6-(furan-3-yl)-2-(3H-imidazo[4,5-c]pyridin-3-yl)-N...)
Affinity DataIC50:  165nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194000(3-(2-(3H-imidazo[4,5-c]pyridin-3-yl)-6-((S)-1-phen...)
Affinity DataIC50:  167nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194006(6-(3-(dimethylamino)phenyl)-2-(3H-imidazo[4,5-c]py...)
Affinity DataIC50:  167nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194013((R)-1-(2-(3H-imidazo[4,5-c]pyridin-3-yl)-6-((S)-1-...)
Affinity DataIC50:  180nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194014(2-(3H-imidazo[4,5-c]pyridin-3-yl)-6-(1-methyl-1H-p...)
Affinity DataIC50:  245nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193997(6-(furan-3-yl)-2-(3H-imidazo[4,5-c]pyridin-3-yl)-N...)
Affinity DataIC50:  446nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194006(6-(3-(dimethylamino)phenyl)-2-(3H-imidazo[4,5-c]py...)
Affinity DataIC50:  470nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132420(3-((1H-pyrrol-2-yl)methylene)-5-(pyridin-3-yl)indo...)
Affinity DataIC50:  600nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193996(2-(1H-imidazo[4,5-c]pyridin-1-yl)-N-((S)-1-phenyle...)
Affinity DataIC50:  700nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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