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Found 928 with Last Name = 'jayaram' and Initial = 'h'
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19263(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 33...)
Affinity DataKi:  1nM ΔG°:  -51.4kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM50338536(CHEMBL1683637 | [({[(2S,3R,4S,5S)-5-(6-amino-2-eth...)
Affinity DataKi:  1nMAssay Description:Inhibition of human IMPDH1 by SpectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlcohol dehydrogenase E/S chain(Equus caballus)
Cornell University

Curated by ChEMBL
LigandPNGBDBM50368629(CHEMBL2368671)
Affinity DataKi:  1.10nMAssay Description:Inhibition of horse liver alcohol dehydrogenase enzyme by Non-competitive inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM50338539(CHEMBL1683640 | Mycophenolic 2-ethyladenosin-5'-yl...)
Affinity DataKi:  5nMAssay Description:Inhibition of human IMPDH1 by SpectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19257(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 27...)
Affinity DataKi:  7nM ΔG°:  -46.5kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataKi:  7nMAssay Description:Inhibition of human IMPDH2 by SpectrophotometerMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataKi:  7nM ΔG°:  -46.5kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataKi:  10nMAssay Description:Inhibition of human IMPDH 2More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataKi:  10nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataKi:  10nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19261(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 31...)
Affinity DataKi:  10nM ΔG°:  -45.7kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM50338537(CHEMBL1683638 | Tiazofurin-5'-yl-2-ethyladenosin-5...)
Affinity DataKi:  13nMAssay Description:Inhibition of human IMPDH1 by SpectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50338536(CHEMBL1683637 | [({[(2S,3R,4S,5S)-5-(6-amino-2-eth...)
Affinity DataKi:  14nMAssay Description:Inhibition of human IMPDH2 by SpectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19263(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 33...)
Affinity DataKi:  14nM ΔG°:  -44.8kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM50338538(CHEMBL1683639 | {[(2S,3R,4S,5S)-5-(6-Amino-2-ethyl...)
Affinity DataKi:  16nMAssay Description:Inhibition of human IMPDH1 by SpectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19267(CHEMBL392204 | Mycophenolic Adenine Dinucleotide (...)
Affinity DataKi:  16nM ΔG°:  -44.5kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19255(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 25...)
Affinity DataKi:  19nM ΔG°:  -44.1kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19256(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 26...)
Affinity DataKi:  20nM ΔG°:  -43.9kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM50338541(((((2S,3R,4S,5S)-5-(6-amino-9H-purin-9-yl)-3,4-dih...)
Affinity DataKi:  20nMAssay Description:Inhibition of human IMPDH1 by SpectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM50192467(CHEMBL384114 | P1-[7-hydroxy-6-(ethyl-2-yl)-5-meth...)
Affinity DataKi:  20nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50369348(CHEMBL606286)
Affinity DataKi:  21nMAssay Description:The compound was tested for the inhibition towards IMP(Inosine 5'-monophosphate) substrate of Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università di Camerino

Curated by ChEMBL
LigandPNGBDBM50241447((2R,3R,4S,5R)-2-(6-(furan-2-ylmethylamino)-9H-puri...)
Affinity DataKi:  22nMAssay Description:Inhibition of human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50338539(CHEMBL1683640 | Mycophenolic 2-ethyladenosin-5'-yl...)
Affinity DataKi:  24nMAssay Description:Inhibition of human IMPDH2 by SpectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50369348(CHEMBL606286)
Affinity DataKi:  26nMAssay Description:The compound was tested for the inhibition towards NMD (Nicotinamide adenine dinucleotide) substrate of Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19257(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 27...)
Affinity DataKi:  27nM ΔG°:  -43.2kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50228085(CHEMBL238461 | N-hydroxy-6-(4-hydroxy-6-methoxy-7-...)
Affinity DataKi:  30nMAssay Description:Inhibition of human IMPDH 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50338537(CHEMBL1683638 | Tiazofurin-5'-yl-2-ethyladenosin-5...)
Affinity DataKi:  30nMAssay Description:Inhibition of human IMPDH2 by SpectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM50369348(CHEMBL606286)
Affinity DataKi:  33nMAssay Description:The compound was tested for the inhibition towards IMP(Inosine 5'-monophosphate) substrate of Inosine-5'-monophosphate dehydrogenase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataKi:  33nM ΔG°:  -42.7kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataKi:  33nMAssay Description:Inhibition of human IMPDH1 by SpectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50338553(6-(-4-((1-(((2S,3R,4S,5S)-5-(6-amino-9H-purin-9-yl...)
Affinity DataKi:  34nMAssay Description:Inhibition of human IMPDH2 by SpectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50338541(((((2S,3R,4S,5S)-5-(6-amino-9H-purin-9-yl)-3,4-dih...)
Affinity DataKi:  37nMAssay Description:Inhibition of human IMPDH2 by SpectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50192467(CHEMBL384114 | P1-[7-hydroxy-6-(ethyl-2-yl)-5-meth...)
Affinity DataKi:  37nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19267(CHEMBL392204 | Mycophenolic Adenine Dinucleotide (...)
Affinity DataKi:  38nM ΔG°:  -42.4kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50338538(CHEMBL1683639 | {[(2S,3R,4S,5S)-5-(6-Amino-2-ethyl...)
Affinity DataKi:  38nMAssay Description:Inhibition of human IMPDH2 by SpectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50338550(CHEMBL1683752 | Mycophenolic ethylenephosphonate-5...)
Affinity DataKi:  39nMAssay Description:Inhibition of human IMPDH2 by SpectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataKi:  40nMAssay Description:Inhibition of human IMPDH 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataKi:  40nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataKi:  40nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAdenosine receptor A3(Homo sapiens (Human))
Università di Camerino

Curated by ChEMBL
LigandPNGBDBM50241166((2R,3R,4S,5R)-2-(6-(benzylamino)-9H-purin-9-yl)-5-...)
Affinity DataKi:  41.3nMAssay Description:Inhibition of human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50338552(6-(-4-(4-((((2S,3R,4S,5S)-5-(6-amino-9H-purin-9-yl...)
Affinity DataKi:  44nMAssay Description:Inhibition of human IMPDH2 by SpectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19258(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 28...)
Affinity DataKi:  45nM ΔG°:  -41.9kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19259(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 29...)
Affinity DataKi:  45nM ΔG°:  -41.9kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM19261(Tiazofurin Adenine Dinucleotide (TAD) Analogue, 31...)
Affinity DataKi:  49nM ΔG°:  -41.7kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50338540(((2S,3R,4S,5S)-5-(6-amino-9H-purin-9-yl)-3,4-dihyd...)
Affinity DataKi:  60nMAssay Description:Inhibition of human IMPDH2 by SpectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50192469(CHEMBL215311 | P1-(adenosin-5'-yl)methylenephospho...)
Affinity DataKi:  60nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università di Camerino

Curated by ChEMBL
LigandPNGBDBM50241446((2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-(thiophen-2-y...)
Affinity DataKi:  60nMAssay Description:Inhibition of human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM50369348(CHEMBL606286)
Affinity DataKi:  62nMAssay Description:The compound was tested for the inhibition towards NMD (Nicotinamide adenine dinucleotide) substrate of Inosine-5'-monophosphate dehydrogenase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM19266(CHEMBL410745 | Mycophenolic Adenine Dinucleotide (...)
Affinity DataKi:  66nM ΔG°:  -41.0kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota At Twin Citiies

LigandPNGBDBM50338552(6-(-4-(4-((((2S,3R,4S,5S)-5-(6-amino-9H-purin-9-yl...)
Affinity DataKi:  70nMAssay Description:Inhibition of human IMPDH1 by SpectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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