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Found 1799 with Last Name = 'pinard' and Initial = 'e'
TargetIntegrin alpha-5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM10484(US11091471, Example RO-301 | US8846719, 301)
Affinity DataKi:  0.200nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIntegrin alpha-5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513334(US11091471, Example RE-B)
Affinity DataKi:  0.400nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513240(6-((5-methyl-3-(6-methylpyridazin-3-yl)isoxazol-4-...)
Affinity DataKi:  0.400nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513241(N-((1S)-1-(hydroxymethyl)butyl)-6-((5-methyl-3-(6-...)
Affinity DataKi:  0.800nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM133559(US11091471, Example RO-251 | US8846719, 251)
Affinity DataKi:  1nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIntegrin alpha-5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM133580(US11091471, Example RO-272 | US8846719, 272)
Affinity DataKi:  1nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513325(6-((5-methyl-3-(6-methylpyridazin-3-yl)isoxazol-4-...)
Affinity DataKi:  1nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513187(5-methyl-6-((5-methyl-3-(6-methylpyridin-3-yl)isox...)
Affinity DataKi:  1.20nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513040(N-ethyl-6-((5-methyl-3-(6-methyl-3-pyridyl)isoxazo...)
Affinity DataKi:  1.40nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513191(5-methyl-6-((5-methyl-3-(6-methylpyridin-3-yl)isox...)
Affinity DataKi:  2.40nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513297(6-((5-cyclopropyl-3-(6-methylpyridazin-3-yl)isoxaz...)
Affinity DataKi:  2.60nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513332(US11091471, Example RO-094)
Affinity DataKi:  2.90nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513324(6-((5-(fluoromethyl)-3-(6-methylpyridazin-3-yl)iso...)
Affinity DataKi:  3nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513146(N-methyl-6-((5-methyl-3-(6-methylpyridin-3-yl)isox...)
Affinity DataKi:  3.5nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513121(6-((5-methyl-3-(6-methylpyridin-3-yl)isoxazol-4-yl...)
Affinity DataKi:  4.40nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513243(N-(4-methyl-1,1-dioxidotetrahydro-2H-thiopyran-4-y...)
Affinity DataKi:  4.60nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513175((6-((5-methyl-3-(6-methylpyridin-3-yl)isoxazol-4-y...)
Affinity DataKi:  4.60nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513274(4-methoxy-6-((5-methyl-3-(6-methylpyridin-3-yl)iso...)
Affinity DataKi:  4.70nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513032(6-((5-methyl-3-(6-methyl-3-pyridyl)isoxazol-4-yl)m...)
Affinity DataKi:  4.80nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513248(N-(1-isopropylazetidin-3-yl)-6-((5-methyl-3-(6-met...)
Affinity DataKi:  4.90nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513281(N-((1R,3S)-3-hydroxy-3-(trifluoromethyl)cyclopenty...)
Affinity DataKi:  5nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513210(6-((5-methyl-3-(6-methylpyridin-3-yl) isoxazol-4-y...)
Affinity DataKi:  5nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513081(N-((3S)-1,1-dioxothiolan-3-yl)-6-((5-methyl-3-(6-m...)
Affinity DataKi:  5.20nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513103(N-cyclopropyl-6-((5-methyl-3-(6-methylpyridin-3-yl...)
Affinity DataKi:  5.20nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513201(5-((5-methyl-3-(6-methyl-3-pyridyl)isoxazol-4-yl)m...)
Affinity DataKi:  5.20nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513284(N-((1RS,3RS)-3-hydroxycyclopentyl)-6-((5-methyl-3-...)
Affinity DataKi:  5.30nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513088(N-(1,1-dioxothian-4-yl)-6-((5-methyl-3-(6-methylpy...)
Affinity DataKi:  5.40nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513223(2-(1,1-dioxothian-4-yl)-6-((5-methyl-3-(6-methylpy...)
Affinity DataKi:  5.5nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513285(US11091471, Example 153 | trans-N-(4-hydroxycycloh...)
Affinity DataKi:  5.5nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513179((3-hydroxyazetidin-1-yl)(6-((5-methyl-3-(6-methylp...)
Affinity DataKi:  5.80nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513123((RS)óN-(1,1-dioxothiolan-3-yl)-6-((5-methyl-3-(6-m...)
Affinity DataKi:  5.80nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513289(3-oxa-6-azabicyclo[3.1.1]heptan-6-yl(6-((5-methyl-...)
Affinity DataKi:  6nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513260(6-((3-(6-cyclopropyl-3-pyridyl)-5-methyl-isoxazol-...)
Affinity DataKi:  6.10nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513225(2-((5-methyl-3-(6-methyl-3-pyridyl)isoxazol-4-yl)m...)
Affinity DataKi:  6.20nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513216(N-(1-(hydroxymethyl)cyclopropyl)-6-((5-methyl-3-(6...)
Affinity DataKi:  6.30nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513244((2,2-dioxido-2-thia-6-azaspiro[3.3]heptan-6-yl)(6-...)
Affinity DataKi:  6.5nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513144((RS)-6-((5-methyl-3-(6-methylpyridin-3-yl)isoxazol...)
Affinity DataKi:  6.60nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513231((R)-6-((5-methyl-3-(6-methylpyridin-3-yl)isoxazol-...)
Affinity DataKi:  6.80nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513170((6-((5-methyl-3-(6-methylpyridin-3-yl)isoxazol-4-y...)
Affinity DataKi:  7.10nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513161(US11091471, Example 57 | azetidin-1-yl(6-((5-methy...)
Affinity DataKi:  7.20nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513228(2-(4,4-difluorocyclohexyl)-6-((5-methyl-3-(6-methy...)
Affinity DataKi:  7.20nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513178((3-fluoroazetidin-1-yl)(6-((5-methyl-3-(6-methylpy...)
Affinity DataKi:  7.20nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513042((S)óN-(1-hydroxypentan-2-yl)-6-((5-methyl-3-(6-met...)
Affinity DataKi:  7.30nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513128(N-isopropyl-6-((5-methyl-3-(6-methylpyridin-3-yl)i...)
Affinity DataKi:  7.5nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513298(US11091471, Example 166 | trans-N-((1RS,3RS)-3-met...)
Affinity DataKi:  7.60nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513127(N-ethyl-6-((5-methyl-3-(6-methylpyridin-3-yl)isoxa...)
Affinity DataKi:  7.60nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513151(6-((5-methyl-3-(6-methyl-3-pyridyl)isoxazol-4-yl)m...)
Affinity DataKi:  7.60nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513183(N-(1-cyanocyclopropyl)-6-((5-methyl-3-(6-methylpyr...)
Affinity DataKi:  7.70nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513288(N-(3-hydroxycyclohexyl)-6-((5-methyl-3-(6-methylpy...)
Affinity DataKi:  7.80nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM513159((3-hydroxy-3-methylazetidin-1-yl)(6-((5-methyl-3-(...)
Affinity DataKi:  7.90nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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