Compile Data Set for Download or QSAR
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Found 11 of ic50 for monomerid = 10020
TargetAromatase(Homo sapiens (Human))
University of Bath

LigandPNGBDBM10020((2-bromo-4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl...)
Affinity DataIC50:  0.820nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University of Bath

LigandPNGBDBM10020((2-bromo-4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl...)
Affinity DataIC50:  0.820nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University of Bath

LigandPNGBDBM10020((2-bromo-4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl...)
Affinity DataIC50:  0.820nMAssay Description:Inhibitory activity to dihydrofolate reductase in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAromatase(Homo sapiens (Human))
University of Bath

LigandPNGBDBM10020((2-bromo-4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl...)
Affinity DataIC50:  0.820nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University of Bath

LigandPNGBDBM10020((2-bromo-4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl...)
Affinity DataIC50:  0.820nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))TBA
LigandPNGBDBM10020((2-bromo-4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl...)
Affinity DataIC50:  39nMAssay Description:Inhibitory activity against dihydrofolate reductase in rat liverMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSteryl-sulfatase(Homo sapiens (Human))TBA
LigandPNGBDBM10020((2-bromo-4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl...)
Affinity DataIC50:  39nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))TBA
LigandPNGBDBM10020((2-bromo-4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl...)
Affinity DataIC50:  39nMAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))TBA
LigandPNGBDBM10020((2-bromo-4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl...)
Affinity DataIC50:  39nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))TBA
LigandPNGBDBM10020((2-bromo-4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl...)
Affinity DataIC50:  39nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Bath

LigandPNGBDBM10020((2-bromo-4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl...)
Affinity DataIC50:  137nMpH: 7.8 T: 2°CAssay Description:The in vitro inhibition of carbonic anhydrase was assessed by a colorimetric assay. Carbonic anhydrase-catalysed hydrolysis of p-nitrophenyl acetate ...More data for this Ligand-Target Pair