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Found 4 of ic50 for monomerid = 101763
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM101763(CHEMBL2057909 | US8530490, 23)
Affinity DataIC50:  40nMAssay Description:Inhibition of human dUTPase assessed as production of [5-3H]dUMP from [5-3H]dUTP after 15 mins measured by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM101763(CHEMBL2057909 | US8530490, 23)
Affinity DataIC50:  40nMAssay Description:Inhibition of human dUTPase-mediated formation of [5-3H]dUMP expressed in Escherichia coli BL21 (DE3) after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM101763(CHEMBL2057909 | US8530490, 23)
Affinity DataIC50:  50nMAssay Description:The inhibitory activity of the compound against human dUTPase was determined by measuring the production of [5-3H]deoxyuridine monophosphate from [5-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM101763(CHEMBL2057909 | US8530490, 23)
Affinity DataIC50:  50nMpH: 7.4 T: 2°CAssay Description:The inhibitory activity of these compounds of the present invention against human dUTPase was determined by measuring the production of [5-3H]deoxyur...More data for this Ligand-Target Pair
In DepthDetails US Patent