Compile Data Set for Download or QSAR
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Found 4 of ki for monomerid = 102263
TargetOrexin receptor type 2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM102263(US8530648, 200)
Affinity DataKi:  161nMpH: 7.4Assay Description:FLIPR assay using orexin receptor.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM102263(US8530648, 200)
Affinity DataKi:  589nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK cells assessed as inhibition of orexin A-induced Ca2+ accumulation after 1 hr by Fluo-4-AM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM102263(US8530648, 200)
Affinity DataKi:  1.44E+3nMpH: 7.4Assay Description:FLIPR assay using orexin receptor.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM102263(US8530648, 200)
Affinity DataKi:  1.48E+3nMAssay Description:Antagonist activity at human OX1 receptor expressed in CHO cells assessed as inhibition of orexin A-induced Ca2+ accumulation after 1 hr by Fluo-4-AM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed