Compile Data Set for Download or QSAR
maximum 50k data
Found 9 of ic50 for monomerid = 110706
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM110706(US8614206, 139)
Affinity DataIC50:  500nMAssay Description:Inhibition of dopamine receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM110706(US8614206, 139)
Affinity DataIC50:  2.50E+3nMAssay Description:Antagonist activity at alpha 1a adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM110706(US8614206, 139)
Affinity DataIC50:  2.50E+3nMAssay Description:Agonist activity at 5HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM110706(US8614206, 139)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human ERG expressed in HEK293 cells after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM110706(US8614206, 139)
Affinity DataIC50:  4.90E+3nMAssay Description:Antagonist activity at 5HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM110706(US8614206, 139)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of MAP4K4 (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM110706(US8614206, 139)
Affinity DataIC50:  6.30E+3nMAssay Description:Reversible inhibition of CYP3A4 (unknown origin) using testosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM110706(US8614206, 139)
Affinity DataIC50:  7.50E+3nMAssay Description:Reversible inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM110706(US8614206, 139)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of GSK3beta in human human MM1S cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed