Compile Data Set for Download or QSAR
maximum 50k data
Found 11 of ic50 for monomerid = 142234
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM142234(US8933098, 1 | US8933099, 1)
Affinity DataIC50:  5.60nMAssay Description:Antagonist activity against human EP4 expressed in HEK293 cells assessed as inhibition of PGE2-stimulated production of cAMP incubated for 20 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM142234(US8933098, 1 | US8933099, 1)
Affinity DataIC50:  9.80nMT: 2°CAssay Description:In this assay, the inhibitory activity of a test substance against the tyrosine kinase activity of FGFR1 protein is measured.To each well of a flat b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM142234(US8933098, 1 | US8933099, 1)
Affinity DataIC50:  12nMAssay Description:Antagonist activity against rat EP4 assessed as inhibition of PGE2-stimulated production of cAMPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM142234(US8933098, 1 | US8933099, 1)
Affinity DataIC50:  123nMAssay Description:Antagonist activity against EP4 in human whole blood assessed as reversal of PGE2-mediated suppression of LPS-induced TNF-alpha production preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM142234(US8933098, 1 | US8933099, 1)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM142234(US8933098, 1 | US8933099, 1)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM142234(US8933098, 1 | US8933099, 1)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2B6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM142234(US8933098, 1 | US8933099, 1)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM142234(US8933098, 1 | US8933099, 1)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM142234(US8933098, 1 | US8933099, 1)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM142234(US8933098, 1 | US8933099, 1)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed